Carbohydrate Loading in Lowering Perioperative Insulin Resistance in Pediatric Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Carbohydrate loading, Water (Placebo).
- Who it may be relevant to
- Registry conditions: Insulin Resistance. Basic parameters: 2 years — 16 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Indonesia
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Effectiveness of Carbohydrate Loading in Lowering Perioperative Insulin Resistance in Pediatric Patients Undergoing Elective Surgery
Overview
It is a double blinded randomized controlled trial interventional study, examining the effect of carb loading given prior to surgery on preventing post operative insulin resistance in pediatric patients undergoing elective surgery
Detailed description
The tsudy
Interventions
- Other Carbohydrate loading
Subjects, at 1 hour prior to surgery, are given liquid containing Dextrose10% with osmolality of 191,92mOsm/L and energy of 34 kcal/100 cc. The dose is 3 ml/kg body weight - Other Water (Placebo)
Subjects, at 1 hour prior to surgery, are given just water with the dose of 3 ml/kg body weight
Primary outcome measures
- Insulin Resistance [Time frame: measured just before incision and 24 hour after surgery]
Eligibility criteria
Inclusion criteria
- ASA Physical Status I and II
- Able to tolerate enteral feeding
- Subjects are undergoing surgery with general anesthesia
Exclusion criteria
- Subjects consume corticosteroids and insulin
- Subjects have endocrine disorder, gastroesophageal reflux disease and psychiatric disorder
- Subjects are treated with preoperative parenteral nutrition
- The surgical procedure is longer than 4 hours
Drop out Criteria:
\- Intraoperative surgical emergency e.g. massive bleeding
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Other
Study locations
Indonesia · 1 center
- Sardjito General Hospital — Yogyakarta
Identifiers
NCT: NCT07545538 · KE/FK/0951/EC/2024