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Recruiting NCT07540429

ADOLESCENTS IMAGING USING fMRI: Feasibility Study

No phase Interventional Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group Diagnosis of ADHD Using the KSADS-PL for the ADHD Group Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group All Participants Were Euthymic at the Time of Task Administration

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: functional magnetic resonance imaging (fMRI).
Who it may be relevant to
Registry conditions: Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration. Basic parameters: 12 years — 17 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Feasibility Study Using Functional Magnetic Resonance Imaging (fMRI) on Bordeline Personality Disorders in Adolescents

Overview

Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents with BPD. This study aims to increase knowledgements related to neural correlates of BPD and clinical disorders.

Interventions

  • Diagnostic test functional magnetic resonance imaging (fMRI)
    Investigators used fMRI to compare patterns of regional brain activation between three groups of adolescents girls: Six female adolescents meeting criteria for BPD, 6 female adolescents meeting criteria of ADHD and 6 female adolescents without psychiatric disorder were recruited.

Primary outcome measures

  • MRI-Acquired Activation Mapping [Time frame: 2 years]
Secondary outcome measures (1)
  • Feasibility of this study [Time frame: 2 years]

Eligibility criteria

Inclusion criteria

  • Female adolescents meeting DIB-R criteria for BPD group
  • Female adolescents meeting kSADS-PL for ADHD group
  • Female adolescents without any psychologic disorders

Exclusion criteria

  • Any medical history with head trauma, chronic neurologic disease, any contraindications for fRMI, claustrophobia or pregnancy.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Diagnostic

Study locations

France · 1 center
  • EPSM de la Somme — Dury

Publications

  • Guile JM, Boissel L, Alaux-Cantin S, de La Riviere SG. Borderline personality disorder in adolescents: prevalence, diagnosis, and treatment strategies. Adolesc Health Med Ther. 2018 Nov 23;9:199-210. doi: 10.2147/AHMT.S156565. eCollection 2018. PMID 30538595

Identifiers

NCT: NCT07540429 · 2022-A00741-42

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗