Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Menstrual Cycle, Optic Nerve Sheath Diameter, Postoperative Nausea and Vomiting. Basic parameters: 18 years — 45 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Effect of Menstrual Cycle Phase on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
Overview
This observational study aims to evaluate the effect of menstrual cycle phase on optic nerve sheath diameter (ONSD) in women undergoing elective laparoscopic gynecologic surgery. Patients will be grouped according to menstrual cycle phase as follicular or luteal. ONSD measurements will be performed perioperatively, and postoperative nausea and vomiting as well as postoperative cognitive function will also be assessed. The study is designed to investigate whether hormonal variations during the menstrual cycle are associated with differences in intracranial pressure reflected by ONSD measurements and postoperative outcomes
Primary outcome measures
- Optic Nerve Sheath Diameter [Time frame: Before induction of anesthesia, during surgery, and at the end of surgery]
Secondary outcome measures (2)
- Postoperative Nausea and Vomiting [Time frame: Within 24 hours after surgery]
- Postoperative Cognitive Function [Time frame: Preoperative period and 24 hours after surgery]
Eligibility criteria
Inclusion criteria
- Female patients aged 18 to 45 years
- Scheduled for elective laparoscopic gynecologic surgery
- Menstrual cycle in the follicular phase or luteal phase
- American Society of Anesthesiologists (ASA) physical status I-II
Exclusion criteria
- Irregular menstrual cycle (e.g., polycystic ovary syndrome, early menopause, hypothalamic amenorrhea)
- Pregnancy or breastfeeding
- Neurological disease associated with intracranial pressure changes
- Glaucoma or another eye disease associated with high intraocular pressure
- Previous brain surgery
- Uncontrolled hypertension or severe cardiovascular disease
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 1 center
- Konya City Hospital — Konya
Identifiers
NCT: NCT07539831 · KSH-ANEST-2025-ONSD-01