Biomechanical Muscle Properties and Balance in Children With Spastic Hemiplegia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: hemiplegic group, normal group.
- Who it may be relevant to
- Registry conditions: Spastic Hemiplegia. Basic parameters: 6 years — 12 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Muscle Biomechanical Properties and Postural Control During Static and Dynamic Standing in Children With Spastic Hemiplegia
Overview
this study will be conducted to investigate the relationship between muscle tone and dynamic stiffness during balance control and postural stability in children with spastic hemiplegia
Detailed description
Cerebral palsy (CP) is a neurodevelopmental disorder that affects muscle tone, posture and motor skills. It is the most common cause of motor disability in infants and children. It describes a group of permanent disorders resulting from non-progressive injury to the fetal or infant developing brain. Although the disorder itself is non-progressive, the clinical manifestations change over time as the brain matures.Children with hemiplegic CP often have difficulty performing voluntary movements due to decreased muscle strength and abnormal muscle tone. As a result, the child are unable to generate the necessary force to maintain their positions against gravity, leading to abnormal posture and balance. Myotonometers are compact, noninvasive tools that swiftly and efficiently gauge the biomechanical characteristics of soft tissues. In typically developing (TD) children, in children with developmental disabilities, and in individuals affected by stroke, it was found to be reliable.Balance is the capacity to preserve equilibrium against gravity during upright postures by maintaining the COM over the center of the BOS. It involves reacting to internal (voluntary movements) and external disturbing forces rapidly and effectively through different postural mechanisms to recover stability. It can be classified into static (maintaining the BOS with minimum movements), and dynamic (maintaining the BOS during different body movements). A comprehensive examination of muscle tone in UCP children can help us understand its impact on motor function and develop more targeted therapeutic interventions.
This understanding can have important clinical implications for treatment efficacy, rehabilitation strategies, and neurophysiological assessments. Addressing muscle tone abnormalities provides a more complete picture of the motor impairments and guides the development of individualized treatment plans, ultimately improving functional outcomes for children with UCP. Therefore, this study aimed to investigate the biomechanical properties, such as muscle tone and stiffness in the lower limb muscles of children with UCP compared with their TD peers. Additionally, investigators explored the associations between these properties and balance control in children with hemiplegia.
Interventions
- Other hemiplegic group
twenty children with mild degree of spasticity ranged from 1 to 1+ according to Modified Ashworth Scale and Their motor function will be at level I and II according to Gross Motor Function Classification System.Their age will range from 6 to 12 years. - Other normal group
twenty normal children with no history of neurological or musculoskeletal disorders.
Primary outcome measures
- oscillatory frequency [Time frame: up to one day]
- Limits of stability [Time frame: up to one day]
- center of pressure [Time frame: up to one day]
Secondary outcome measures (5)
- muscle dynamic stiffness [Time frame: up to one day]
- The modified clinical test of sensory integration of balance [Time frame: up to one day]
- muscle elasticity [Time frame: up to one day]
- mechanical stree relaxation time [Time frame: up to one day]
- muscle viscoelastic property [Time frame: up to one day]
Eligibility criteria
Inclusion criteria
- Their age will range from 6 to 12 years.
- Mild degree of spasticity ranged from 1 to 1+ according to Modified Ashworth Scale
- Their motor function will be at level I and II according to Gross Motor Function Classification System GMFCS
- They will be able to follow instructions during evaluation procedures.
- Their caregivers are of a good command of the English language.
Exclusion criteria
- Botulinum toxin injections in the last 6 months.
- The presence of visual or auditory impairments.
- Surgical interference in upper, lower limbs and/or spine.
- Muscloskeletal problems or fixed deformities in the spine and/or upper or/and lower extremities.
- Seizures.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Other
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07538297 · P.T.REC/012/006025