The Prognostic Value of Cardiopulmonary Exercise Testing Parameters in Patients With Coronary Heart Disease: A Retrospective Cohort Study(CPETPCAD)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Coronary Heart Disease (CHD). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Prognostic Value of Cardiopulmonary Exercise Testing Parameters in Patients With Coronary Heart Disease: A Retrospective Cohort Study
Overview
Parameters related to cardiopulmonary exercise testing (CPET) are important objective indicators for evaluating cardiopulmonary function in patients with coronary heart disease. However, the clinical application of CPET parameters in the prognostic assessment of patients with coronary heart disease remains unclear. This is a retrospective cohort study designed to systematically collect real-world clinical data and long-term follow-up outcomes of patients with coronary heart disease. Through standardized follow-up, this study will investigate the association between CPET parameters and adverse clinical outcomes in patients with coronary heart disease, as well as the relevant risk factors.
Primary outcome measures
- Cumulative incidence of Major Adverse Cardiovascular Events (MACE) [Time frame: 1 year]
Secondary outcome measures (1)
- All-cause mortality [Time frame: 1 year]
Eligibility criteria
Inclusion criteria
- Our hospital has diagnosed coronary heart disease and conducted cardiopulmonary exercise tests.
- Patients with complete clinical data.
Exclusion criteria
- Uncontrolled heart failure (NYHA classification Ⅲ-IV grade).
- Complications, such as moderate to severe anemia, tumors and lung diseases.
- Complicated with valvular heart disease.
- Unable to reach the anaerobic threshold during exercise.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Zhang N, Maitudi M, Lu W. Combined Effects of Nicorandil and Enhanced External Counterpulsation on Coronary Microcirculation and Exercise Capacity in Patients With Coronary Slow Flow Phenomenon: A Randomized, Controlled, 3-Arm Trial. Clin Ther. 2026 Jun 30:S0149-2918(26)00216-X. doi: 10.1016/j.clinthera.2026.06.004. Online ahead of print. PMID 42379943
Identifiers
NCT: NCT07534410 · K202512-44