Vagus Nerve Stimulation for Reaction Time
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: vagus nerve stimulation.
- Who it may be relevant to
- Registry conditions: Healthy Subjects (HS). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Enhancing Reaction Time Through Non-Invasive Vagus Nerve Stimulation
Overview
Non-Invasive Vagus Nerve Stimulation will be provided to the participants using a transcutaneous electrical nerve stimulation (TENS) unit, a routine physical therapy intervention by the faculty researcher who is a licensed physical therapist. The electrodes will be clipped to ear over the vagus nerve distribution area. The parameters will be 30 Hz, 250 us, 5 minutes, at tolerance (no pain). Reaction time will test collected pre and post the stimulation using online reaction time testing platform.
Interventions
- Device vagus nerve stimulation
Non-Invasive Vagus Nerve Stimulation will be provided to the participants using a transcutaneous electrical nerve stimulation (TENS) unit, a routine physical therapy intervention by the faculty researcher who is a licensed physical therapist. The electrodes will be clipped to ear over the vagus nerve distribution area. The parameters will be 30 Hz, 250 us, 5 minutes, at tolerance (no pain)
Primary outcome measures
- Reaction time [Time frame: Baseline and immediately after the intervention.]
Eligibility criteria
Inclusion criteria
- Healthy participants over the age of 18
- did not receive vagus nerve stimulation previously
Exclusion criteria
- alcohol or drug abuse
- metal in the skull
- implanted cardiac or cranial devices
- Women during 3 trimester of pregnancy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Basic science
Study locations
United States · 1 center
- Youngstown State University — Youngstown
Publications
- Camargo L, Gianlorenco AC, Pacheco-Barrios K, Pichardo E, Costa V, Choi H, Song JJ, Fregni F. The effects of non-invasive transcutaneous auricular vagus nerve stimulation on resting-state delta oscillation: a randomized, double-blinded, sham-control trial. Sci Rep. 2025 Oct 3;15(1):34531. doi: 10.1038/s41598-025-17821-5. PMID 41044114
Identifiers
NCT: NCT07528742 · 2026-218