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Recruiting NCT07528469

The Effects of PeptiStrong and Whey on Muscle Function In Older Adults

No phase Interventional Healthy Ageing Protein Supplementation Muscle Health Muscle Function

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: PeptiStrong + whey protein, Whey protein.
Who it may be relevant to
Registry conditions: Healthy Ageing, Protein Supplementation, Muscle Health, Muscle Function. Basic parameters: 60 years — 85 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United Kingdom
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

The Effects of PeptiStrong and Low Dose Whey Protein Versus High Dose Whey Protein Alone on Muscle Function In Older Adults

Overview

Examining the effects of PeptiStrong and protein on muscle function in older adults

Detailed description

The aim of this study is to compare two protein drinks containing whey protein (derived from milk) in healthy adults aged 60 to 85 years. One group will consume a standard whey protein drink (20g), while the other group will consume a drink with half the total protein dose (10g) made of whey protein and PeptiStrong, a fava bean hydrolysate containing bioactive peptides.

The study will assess whether the lower protein drink containing PeptiStrong will lead to equal or greater improvements than the standard drink in physical function, such as the ability to stand up from a chair, walk at a normal pace, maintain balance, and grip strength. The study will also examine markers related to inflammation, fatigue, and quality of life.

The intended value of this research is to improve understanding of how targeted nutritional strategies may help maintain or improve muscle function in older adults. The findings may help inform future nutritional recommendations and the development of practical dietary interventions aimed at supporting healthy ageing and independence.

Interventions

  • Dietary supplement PeptiStrong + whey protein
    Fava bean protein hydrolysate containing bioactive peptides mixed with whey protein as dry powder for drinkable protein shake
  • Dietary supplement Whey protein
    Whey protein as dry powder for drinkable protein shake

Primary outcome measures

  • Hand Grip Strength via hand held dynamometer [Time frame: Baseline to Week 4]
Secondary outcome measures (10)
  • Chair Stand Test - Part of short performance physical battery [Time frame: Baseline to week 4]
  • Gait Speed as part of short performance physical battery [Time frame: Baseline to week 4]
  • 6 Minute Walking Endurance Test [Time frame: Baseline to week 4]
  • Balance test as part of short performance physical battery [Time frame: Baseline to week 4]
  • Balance assessment via force plates [Time frame: Baseline to week 4]
  • Quality of Life via the Sarcopenia Quality of Life (SarQoL®) Questionnaire [Time frame: Baseline to week 4]
  • Fatigue via Multidimensional Fatigue Inventory Questionnaire [Time frame: Baseline to week 4]
  • C-reactive protein (CRP) via blood test [Time frame: Baseline to week 4]
  • Interleukins via blood test [Time frame: Baseline to week 4]
  • Body composition: Muscle mass and body fat via bioelectrical impedance analysis [Time frame: Baseline to week 4]

Eligibility criteria

Inclusion criteria

  • Men and women aged 60 to 85 years at the time of enrolment
  • Community-dwelling (living independently or with minimal assistance)
  • Able to walk independently (with or without a walking aid) and complete simple physical function tests (such as standing up from a chair and walking short distances)
  • Willing and able to attend two study visits at the research facility (baseline and end of study)
  • Willing and able to consume a protein drink containing whey protein (derived from milk) once daily for 30 days
  • Able to understand the study information and provide written informed consent

Exclusion criteria

  • Any known food allergy or intolerance to fava bean protein or milk protein
  • Diagnosed kidney disease or any medical condition where increased protein intake is contraindicated
  • Yes to any of the answers on the "Older Adult Functional Assessment Screening Questionnaire"
  • Individuals with implanted electronic devices
  • Current or recent (within the past 3 months) participation in another clinical research study involving a nutritional or exercise intervention
  • Conditions that significantly impair mobility or balance such that safe completion of the physical function tests is not possible

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Other

Study locations

United Kingdom · 1 center
  • LJMU, Byrom Street — Liverpool

Identifiers

NCT: NCT07528469 · PEPVFH+60/26

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗