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Enrolling by invitation NCT07527871

Emergency Department-Substance Use Screening, Motivational Interviewing and Active Referral Targeting Substance Use Disorder and Overdose Prevention

No phase Interventional Substance Use (Drugs, Alcohol)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: ED-SMART intervention, Substance use information.
Who it may be relevant to
Registry conditions: Substance Use (Drugs, Alcohol). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

ED-SMART: Emergency Department-Substance Use Screening, Motivational Interviewing and Active Referral Targeting Substance Use Disorder and Overdose Prevention

Overview

The purpose of this research study is to learn if an emergency department screening and telehealth intervention reduces substance use among individuals receiving emergency department treatment at The Ohio State University Wexner Medical Center.

Interventions

  • Behavioral ED-SMART intervention
    The ED-SMART intervention will include: (i) a brief (approximately 15 minutes) counseling session in the emergency department and (ii) five, monthly brief counseling sessions (approximately 15 to 30 minutes) delivered by telehealth. These sessions will focus on creating individualized strategies to help participants reach their alcohol and substance use reduction goals
  • Behavioral Substance use information
    The substance use information condition will receive printed health information covering information about substance use (e.g., definitions, hazards, potential for addiction, injury, and other consequences). Research staff will also discuss ways to utilize primary care or establish care with a primary care provider to provide ongoing follow-up.

Primary outcome measures

  • Self-reported substance use [Time frame: From baseline to the sixth month follow-up assessment]
Secondary outcome measures (5)
  • Self-reported substance use quantity [Time frame: From baseline to the six month follow-up]
  • Incidence of positive substance use disorder screen [Time frame: From baseline to the six month follow-up]
  • Toxicology assays for substance use [Time frame: From baseline to the six month follow-up assessment]
  • Self-reported healthcare utilization [Time frame: Baseline to the six month follow-up assessment]
  • Fatal and non-fatal overdose [Time frame: Baseline to the six month follow-up assessment]

Eligibility criteria

Inclusion criteria

  • Adult at least 18 years of age
  • Capacity and willingness to participate (including reliable phone or internet access for counseling session)
  • Lower or Moderate Risk score on one or more substance use types on National Institute on Drug Abuse (NIDA)-Modified Alcohol, Smoking, and Substance Use Involvement Test (ASSIST). Participants may also endorse alcohol use in conjunction with substance use as indicated by an Alcohol Use Disorder Identification Test-Concise (AUDIT-C) score of Moderate Risk.

Exclusion criteria

  • A priori participant request for participation
  • Previously enrolled in this or other study of substance use disorder prevention
  • Language other than English
  • Expected/actual ED disposition of hospitalization or non-independent status
  • Prisoner at time of enrollment
  • Known to be pregnant at time of enrollment
  • Past substance use disorder or substance use treatment
  • High risk score for one or more substances on the NIDA-Modified ASSIST or problematic alcohol use alone

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

United States · 1 center
  • The Ohio State University Wexner Medical Center — Columbus

Identifiers

NCT: NCT07527871 · STUDY2025-00000054 · U01CE003825

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗