Comparison of the Analgesic Efficacy of Adductor Canal Block and Combined Adductor Canal Block Plus IPACK Block in Knee Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Adductor Canal Block Group (Group I), Adductor Canal + iPACK Block Group (Group II)".
- Who it may be relevant to
- Registry conditions: Knee Arthroplasty, Total. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Block Combined With Local Anesthetic Infiltration Between the Popliteal Artery and the Capsule of the Knee (IPACK) in Patients Undergoing Knee Surgery
Overview
To evaluate the effectiveness of Adductor Canal Block and combined Adductor Canal plus IPACK block in reducing postoperative pain and analgesic requirements in patients undergoing knee surgery.
Detailed description
In total knee arthroplasty, ultrasound-guided Adductor canal block or Adductor Canal block combined with local anesthetic infiltration between the popliteal artery and the capsule of the knee (IPACK) will provide adequate postoperative analgesia.
Interventions
- Procedure Adductor Canal Block Group (Group I)
All patients in Group I will receive a preoperative adductor canal block. In all groups, an intravenous patient-controlled analgesia device containing morphine will be administered for postoperative pain management. - Procedure Adductor Canal + iPACK Block Group (Group II)"
All patients in Group II will receive a preoperative adductor canal block combined with an iPACK block. Postoperatively, all patients in both groups will be provided with intravenous patient-controlled analgesia containing morphine for pain management.
Primary outcome measures
- opioid consumption [Time frame: 24 hours after surgery]
- Verbal analog Pain Scores on rest and movement [Time frame: 24 hours after surgery]
Secondary outcome measures (1)
- incidences of adverse effects (like nausea and vomiting) [Time frame: 24 hours after surgery]
Eligibility criteria
Inclusion criteria
- ASA (American Society of Anesthesiologists) I- ASA II-ASA III Patients
Exclusion criteria
- history of allergy to the study medication
- refusal to participate
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 2 centers
- Sibel Pehlivan — Kayseri
- Sibel Seckin Pehlivan — Kayseri
Publications
- Shoni M, Samineni AV, Salavati S, Mikkilineni N, Wang A, Abdeen A, Freccero D. Combined Single-Shot Infiltration Between the Popliteal Artery and Capsule of the Knee and Adductor Canal Block With Bupivacaine, Dexmedetomidine, and Dexamethasone for Total Knee Arthroplasty: A Propensity-Matched Analysis. Arthroplast Today. 2023 Dec 28;25:101292. doi: 10.1016/j.artd.2023.101292. eCollection 2024 Feb. PMID 38235397
- Mariano ER, Kim TE, Wagner MJ, Funck N, Harrison TK, Walters T, Giori N, Woolson S, Ganaway T, Howard SK. A randomized comparison of proximal and distal ultrasound-guided adductor canal catheter insertion sites for knee arthroplasty. J Ultrasound Med. 2014 Sep;33(9):1653-62. doi: 10.7863/ultra.33.9.1653. PMID 25154949
Identifiers
NCT: NCT07526831 · 2026\115