GLOW Study: Effects of Triple Protein in Women
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Triple protein support, Placebo.
- Who it may be relevant to
- Registry conditions: Healthy Women. Basic parameters: 30 years — 60 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
GLOW Study: A Randomized Trial to Evaluate the Effects of Triple Support Protein on Glucose, Lifestyle, and Overall Well-being in Women
Overview
This single-site, randomized, blinded, placebo-controlled study will evaluate whether 4 weeks of daily Triple Support Protein powder improves glycemic control and overall well-being in healthy women aged 30-60 years. Participants will undergo baseline testing (DXA, fasting blood, standardized meal test with 2-hour glucose and insulin sampling), complete one acute supervised dose, and then consume a daily supplement for 4 weeks. During the final 14 days, participants will wear a continuous glucose monitor. Outcomes include postprandial glucose AUC, insulin sensitivity, and body composition.
Detailed description
Midlife women experience hormonal changes that can impair metabolic health, sleep, and cognition. Triple plant-based protein powder includes creatine and fiber aimed at glycemic control, muscle support, and satiety. Design: 40 participants randomized (1:1) to Triple Protein Support vs. matched placebo for 4 weeks, with acute and chronic phases, weekly check-ins. Assessments: Baseline and end-of-study DXA and bloods; standardized meal tests with 2-hour glucose/insulin sampling; Analysis: Mixed-model ANOVA for primary and secondary endpoints with α=0.05.
Interventions
- Dietary supplement Triple protein support
Plant based protein + creatine + fiber - Dietary supplement Placebo
Non-caloric matched placebo
Primary outcome measures
- Change in postprandial glucose area under the curve (AUC) [Time frame: Glucose measured over 0-120 minutes starting post standardized meal]
Secondary outcome measures (2)
- Change in insulin sensitivity (HOMA-IR) [Time frame: Baseline, Week 6]
- Change in lean soft tissue [Time frame: Baseline, week 6]
Eligibility criteria
Inclusion criteria
- Females aged 30-60 years.
- BMI 18.5-40 kg/m\^2.
- Recreationally active (≥30 min/wk moderate intensity exercise).
- Healthy and free from disease per health history questionnaire.
- Willing to abstain from caffeine, tobacco, and alcohol for 24 hours before testing days.
Exclusion criteria
- Currently supplementing whey protein.
- Pregnant or nursing.
- Lactose intolerant.
- Currently using creatine monohydrate.
- Severe hearing or speech impairment or inability to speak English
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
United States · 1 center
- Department of Exercise and Sport Science, Applied Physiology Laboratory — Chapel Hill
Identifiers
NCT: NCT07526571 · 25-2541