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Recruiting NCT07522671

Clinical Performance of 3D-Printed Resin and Zirconia Implant Restorations

No phase Interventional Prosthesis User

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: 3D-Printed Resin Restoration (CROWNTEC).
Who it may be relevant to
Registry conditions: Prosthesis User. Basic parameters: 18 years — 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Clinical Performance of 3D-Printed Resin Versus Milled Monolithic Zirconia in Implant-Supported Single Crowns and Short-Span Fixed Partial Dentures: A Randomized Controlled Clinical Trial

Overview

This randomized controlled clinical trial evaluates the clinical performance of 3D-printed resin restorations compared with milled monolithic zirconia in implant-supported single crowns and short-span fixed partial dentures (FPDs). A total of patients requiring one or two implant-supported restorations in the mandibular anterior region were randomly allocated to receive either 3D-printed permanent resin restorations (CROWNTEC) or conventionally milled zirconia prostheses. All restorations were fabricated using a standardized digital workflow and assessed over a 12-month follow-up period. The primary outcome was restoration survival rate, while secondary outcomes included technical complications, peri-implant biological parameters, marginal bone level changes, and patient-reported satisfaction. This study aims to provide clinical evidence regarding the viability of 3D-printed definitive resin materials as an alternative to zirconia in implant prosthodontics.

Detailed description

This study was designed as a parallel-arm randomized controlled clinical trial to compare the clinical performance of implant-supported restorations fabricated using a novel 3D-printed resin material (CROWNTEC) with that of conventionally milled monolithic zirconia. The investigation focused on single crowns and short-span fixed partial dentures (FPDs) in the mandibular anterior region, where functional and esthetic demands are critical.

Participants meeting predefined inclusion criteria were randomly assigned into two intervention groups: a 3D-printed resin group and a zirconia group. All restorations were produced using a fully digital workflow, including intraoral scanning, CAD design, and standardized manufacturing protocols. Prostheses were delivered as either screw-retained or cement-retained restorations, with careful control of occlusion and prosthetic design parameters.

Patients were followed at baseline, 3, 6, and 12 months, with extended follow-up planned up to 24 months. The primary outcome measure was restoration survival, defined as the absence of failure requiring replacement. Secondary outcomes included technical complications such as fracture, chipping, and screw loosening; biological parameters including plaque index, bleeding on probing, and probing depth; and radiographic assessment of marginal bone level changes. Patient-reported outcomes were also evaluated using a visual analog scale to assess satisfaction with esthetics, comfort, and masticatory function.

By directly comparing a novel additive manufacturing material with an established reference standard, this study addresses a critical gap in the literature regarding the clinical applicability of 3D-printed definitive restorations in implant dentistry. The findings are expected to contribute valuable evidence on the performance, limitations, and potential role of 3D-printed resin materials in modern prosthodontic practice.

Interventions

  • Device 3D-Printed Resin Restoration (CROWNTEC)
    Implant-supported single crowns or short-span fixed partial dentures fabricated using 3D-printed permanent resin (CROWNTEC). Restorations are produced using a standardized digital workflow, including intraoral scanning, CAD design, 3D printing at 50 µm layer thickness, post-processing (isopropyl alcohol cleaning, post-curing), finishing, and polishing. Restorations are delivered as screw- or cement-retained prostheses. In addition, Other participants will receive implant-supported single crowns

Primary outcome measures

  • Restoration Survival Rate [Time frame: 12 months]

Eligibility criteria

Inclusion criteria

  • Participants must meet all of the following:
  • Age ≥18 years.
  • Have one or two osseointegrated dental implants requiring prosthetic restoration.
  • Demonstrate stable peri-implant tissues with no signs of inflammation or implant mobility.
  • Maintain good oral hygiene and controlled periodontal status.
  • Require either:
  • A single implant-supported crown, or
  • A short-span (maximum 3-unit) implant-supported fixed partial denture (FPD) supported by two implants in the mandibular anterior region.

Exclusion criteria

  • Participants are excluded if they have any of the following:
  • Severe parafunctional habits (e.g., bruxism).
  • Uncontrolled systemic diseases affecting bone metabolism or healing.
  • Peri-implantitis or compromised implant stability.
  • Requirement for cantilever prostheses or long-span restorations, or FPDs in areas other than the mandibular anterior region.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Mohammed Elsawy — Shibīn al Kawm

Identifiers

NCT: NCT07522671 · ADMNF-00326

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗