Nano Coated Orthodontic Miniscrews for en Mass Retraction of the Upper Arch
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Silver nanoparticles, uncoated titanium miniscrews.
- Who it may be relevant to
- Registry conditions: Class I Malocclusion, Maxillary Prognathism, Orthodontic Tooth Movement. Basic parameters: 14 years — 20 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Evaluation of Silver-Hydroxyapatite Nano-coated Versus Uncoated Orthodontic Miniscrews for en Masse Retraction of the Upper Anterior Segment: A Randomized Clinical Trial
Overview
study will be directed to evaluate silver-hydroxyapatite nano-coated versus uncoated orthodontic miniscrews for en masse retraction of the upper anterior segment.
Detailed description
Silver-hydroxyapatite nanoparticles (Ag-HA NPs) have lately gained popularity in dentistry due to their unique combination of silver antibacterial activity and hydroxyapatite's osteoconductive, remineralizing characteristics. Ag-HA has shown potential in resolving two important clinical issues: infection control and anchoring stability. Coating orthodontic miniscrews with Ag-HA NPs has been demonstrated to reduce peri-implant biofilm growth by their antimicrobial effect, minimizing inflammation, and increasing osseointegration, thus increasing the long-term success of temporary anchoring devices (TADs).
Interventions
- Device Silver nanoparticles
Patients will receive silver-hydroxyapatite nanocoated titanium miniscrews.These miniscrews will be placed in the maxillary bone for en masse retractonof the upper anterior teeth. - Device uncoated titanium miniscrews
Patients will receive conventional uncoated titanium miniscrews of the same dimensions and design as the intervention of the group1, but without nano-coating.
Primary outcome measures
- Assessment of the clinical and radiographically success rate of nanocoated versus uncoated orthodontic miniscrews after en masse retraction [Time frame: about 6 months]
Secondary outcome measures (1)
- Assessment of the rate of en masse retraction of the anterior segment of the upper arch [Time frame: 6 months]
Eligibility criteria
Inclusion criteria
- Class I orthodontic cases with bimaxillary protrusion of the anterior segment of the upper jaw that need at least extraction for orthodontic treatment.
- Age 14-20 years.
- Good oral hygiene with healthy periodontium.
- Need for an absolute skeletal anchorage.
- Systemically healthy patients.
Exclusion criteria
- Patient with craniofacial anomalies (e.g, cleft lip and palate)
- Presence of systemic diseases or syndromes affecting bone metabolism (e.g, osteoporosis, rickets)
- Poor oral hygiene or uncooperative patients.
- Extensive dental caries or untreated periodontal disease.
- History of trauma or surgery affecting the maxilla or mandible.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Faculty of Dental Medicine (Boys), Al-Azhar University — Cairo
Identifiers
NCT: NCT07521267 · nano-coated ortho-miniscrew · EC Ref 1344/765