Condylar Offset and Outcomes in Primary Total Knee Arthroplasty
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Knee Arthritis Osteoarthritis. Basic parameters: 50 years — 85 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Prospective Evaluation of Posterior and Anterior Condylar Offset and Their Impact on Functional Outcomes in Primary Total Knee Arthroplasty
Overview
This prospective cohort study aims to evaluate the effect of posterior condylar offset (PCO) and anterior condylar offset (ACO) changes on functional outcomes after primary total knee arthroplasty (TKA). Standardized imaging and clinical assessment protocols will be used to determine optimal PCO and ACO ranges associated with improved postoperative range of motion, patient-reported outcomes, and reduced anterior knee symptoms.
Primary outcome measures
- Maximum Knee Flexion [Time frame: 12 months postoperatively]
Secondary outcome measures (3)
- Knee Society Score [Time frame: 3,6,12 months postoperatively]
- WOMAC score [Time frame: 3,6,12 months postoperatively]
- Change in Anterior and Posterior Condylar Offset [Time frame: preoperative graphy and postoperative 1st day graphy]
Eligibility criteria
Inclusion criteria
- diagnosis of primary knee osteoarthiritis
- indication of knee arthroplasty
- 50-85 years
- ability t oprovide informed consent and comply with follow up
Exclusion criteria
- revision knee arthroplasty
- inflammatory arthritis
- severe corona deformity (>20 varus/valgus)
- previous knee surgery or fracture
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Zhong Y, Deng Z, Gu C, Li M, Kang Y, Liao W, Zhang Z. The Optimal Variation Range of Posterior Condylar Offset Associated with Positive Clinical Outcomes of Primary Total Knee Arthroplasty: A Retrospective Analysis. Orthop Surg. 2024 Nov;16(11):2708-2713. doi: 10.1111/os.14183. Epub 2024 Aug 6. PMID 39107882
- Xu W, Huang X, Liu J, Zhang Z, Chen Z, Xia T, Yan B, Xu Y. Sagittal parameters after primary TKA affecting knee joint function: a correlative analysis and predictive model construction. J Orthop Surg Res. 2026 Feb 9;21(1):193. doi: 10.1186/s13018-026-06707-5. PMID 41656286
Identifiers
NCT: NCT07517614 · TKA-OFFSET-2026-01