Multimodal Phenotyping In Patients Referred With Acute Cardiac faiLurE
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cardiogenic Shock, Acute Heart Failure (AHF). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Germany
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The goal of this observational study is to learn whether information collected during routine hospital care, together with blood and urine samples, can help doctors better identify different types of cardiogenic shock and better predict outcomes in adults hospitalized with acute heart failure and cardiogenic shock. The main question is whether clinical findings, imaging results, and biomarkers, including sex-specific factors, are associated with the risk of death within 30 days. Participants will not receive an experimental treatment. Researchers will collect data from routine care, collect additional blood and urine samples for biobanking, and follow participants after hospital discharge
Primary outcome measures
- Mortality [Time frame: 30 days]
Secondary outcome measures (3)
- Mortality [Time frame: 6 and 12 months]
- Rehospitalization for heart failure [Time frame: From hospital discharge until 12 months]
- Rehospitalization for cardiac reasons (non-elective) [Time frame: From hospital discharge until 12 months]
Eligibility criteria
Inclusion criteria
- Patients hospitalized with acute heart failure SCAI stage B - E.
Exclusion criteria
- Not capable of providing informed consent due to reasons not attributable to cardiogenic shock
- Cardiogenic shock following cardiothoracic surgery
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Germany · 4 centers
- University Heart Center Freiburg - Bad Krozingen — Bad Krozingen
- University Medical Center Freiburg, Interdisciplinary Medical Intensive Care — Freiburg im Breisgau
- Department for Internal Medicine 8, Clinic for Cardiology and Rhythmology, University Clin — Nuremberg
- Schwarzwald Baar Klinikum Villingen-Schwenningen, Klinik für Kardiologie und Intensivmediz — Villingen-Schwenningen
Identifiers
NCT: NCT07515508 · 24-1041_1-S1