Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Self-administered questionnaire assessment, Semi-structured in-depth interviews (IDIs), Development and refinement of harm reduction model.
- Who it may be relevant to
- Registry conditions: HIV Prevention, Substance Use, Mental Health, Sexually Transmitted Infections (STIs). Basic parameters: from 18 years · Male.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Thailand
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study evaluates the pre-implementation phase of a host-led harm reduction model for men who have sex with men (MSM) engaging in chemsex in Bangkok, Thailand, focusing on understanding harms, contexts, and needs to develop a tailored intervention.
Detailed description
HAMMOCK is a cross-sectional mixed-methods study designed to explore chemsex practices among MSM, including both hosts and guests, as well as key stakeholders such as CSOs, hospital staff, and police.
The study aims to:
* Explore substance-related, sexual health, mental health, and socio-legal harms * Understand the context and dynamics of private chemsex parties * Co-develop a novel host-led harm reduction model * Identify barriers and facilitators to implementation The study includes both quantitative (self-administered questionnaires) and qualitative (in-depth interviews) components and follows a two-phase approach: exploration and preparation phases under the EPIS framework.
Interventions
- Behavioral Self-administered questionnaire assessment
Participants (chemsex party hosts and guests) will complete structured self-administered questionnaires to assess: * Substance use patterns and related harms * Sexual health risks (e.g., condom use, HIV/STI testing, PrEP/ART adherence) * Mental health status using validated tools: * Patient Health Questionnaire-9 (PHQ-9) * Generalized Anxiety Disorder-7 (GAD-7) * Socio-legal harms including stigma and discrimination - Behavioral Semi-structured in-depth interviews (IDIs)
All stakeholders will participate in semi-structured in-depth interviews: * Exploration phase: guided by EPIS framework * Preparation phase: guided by * Theoretical Domains Framework (TDF) (hosts \& guests) * Consolidated Framework for Implementation Research (CFIR) (organizational stakeholders) The interviews aim to: * Identify harms associated with chemsex * Explore current practices and contexts * Identify barriers and facilitators * Inform development and refinement of a harm reducti - Behavioral Development and refinement of harm reduction model
A novel four-pronged harm reduction model will be developed and refined based on quantitative and qualitative findings. Domains include: * Substance use harm reduction * Sexual health harm reduction * Mental health harm reduction * Socio-legal harm reduction
Primary outcome measures
- Substance use-related harm assessed by self-administered questionnaire [Time frame: Baseline (during Exploration phase, prior to model development)]
- Sexual health risk behaviors assessed by self-administered questionnaire [Time frame: Baseline (during Exploration phase, prior to model development)]
- Depression severity assessed by Patient Health Questionnaire-9 (PHQ-9) [Time frame: Baseline (during Exploration phase, prior to model development)]
- Anxiety severity assessed by Generalized Anxiety Disorder-7 (GAD-7) [Time frame: Baseline (during Exploration phase, prior to model development)]
Secondary outcome measures (1)
- Perceived stigma and socio-legal harm assessed by structured questionnaire [Time frame: Baseline (during Exploration phase, prior to model development)]
Eligibility criteria
Inclusion criteria
- MSM aged ≥18 years
- Able to communicate in Thai
- Specific by group:
- Chemsex hosts: hosted ≥2 times in past 6 months
- Chemsex guests: attended ≥2 times in past 6 months
- CSO / hospital / police staff: working ≥3 months in related roles
- Provide informed consent
Exclusion criteria
- Unable to provide informed consent (e.g., under substance influence at consent)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Thailand · 1 center
- Tangerine Clinic, Institute of HIV Research and Innovation — Pathum Wan
Identifiers
NCT: NCT07512869 · IHRI037