Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: diagnosis of APSI, MLSI, OASI.
- Who it may be relevant to
- Registry conditions: Ankle Sprains, Patellofemoral Pain Syndrome. Basic parameters: 20 years — 30 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders: Evidence From Lateral Ankle Sprain and Patellofemoral Pain Syndrome
Overview
Lateral ankle sprain (LAS) and patellofemoral pain syndrome (PFPS) are common musculoskeletal conditions associated with postural instability. However, the direction-specific nature of balance deficits and comparative patterns across these conditions remain unclear. Therefore, the aim of this study is to compare overall, mediolateral, and anteroposterior postural stability indices among individuals with LAS, PFPS, and healthy controls using the Biodex Balance System
Interventions
- Diagnostic test diagnosis of APSI, MLSI, OASI
To compare overall, antero-posterior and mediolateral postural stability indices among individuals with lateral ankle sprain, patellofemoral pain syndrome, and healthy controls using the Biodex Balance System.
Primary outcome measures
- APSI [Time frame: one shot assessment within one week]
- MLSI [Time frame: one shot assessment within one week]
- OASI [Time frame: one shot assessment within one week]
Eligibility criteria
Inclusion criteria
Inclusion criteria for the lateral ankle sprain group will include participants with a clinically confirmed history of unilateral lateral ankle sprain, who are at least three months post-injury to avoid acute inflammatory effects, and who report residual symptoms such as pain or functional limitation. Participants in the patellofemoral pain syndrome group will have a clinical diagnosis of patellofemoral pain syndrome characterized by anterior or retropatellar knee pain aggravated by functional activities such as stair climbing, squatting, or prolonged sitting, with symptoms persisting for at least three months. Healthy control participants will have no history of lower limb musculoskeletal injury, pain, or functional impairment within the past three months and will be matched to the patient groups based on age and sex. All participants across groups will be able to stand independently without assistive devices and will demonstrate sufficient cognitive ability to understand and follow study instructions
Exclusion criteria
Exclusion criteria for all groups will include a history of lower limb fracture or surgery, neurological or vestibular disorders that may affect balance or postural control, uncorrected visual impairments, systemic inflammatory or rheumatological diseases, and metabolic or neurological conditions known to influence neuromuscular performance. Participants currently engaged in structured balance, proprioceptive, or neuromuscular training programs, as well as those taking medications that may affect balance or postural stability, will also be excluded from the study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07508163 · Approved