The Effect of Remotely Delivered Pilates on Physical , and Psychological Outcomes in Individuals With Multiple Sclerosis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Pilates.
- Who it may be relevant to
- Registry conditions: Multiple Sclerosis, Pilates Exercise, Walking, Balance. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Does Remotely Delivered Pilates Influence Physical and Psychological Outcomes in Individuals With Multiple Sclerosis?
Overview
Objectives Objective 1: To determine the effects of a 16-week remotely delivered Pilates intervention on walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS. Objective 2: To examine the impact of a 16-week remotely delivered Pilates intervention on depression \& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS. Aim Aim 1: To assess whether the 16-week remotely delivered Pilates intervention significantly improves walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS Aim 2: To investigate whether the 16-week remotely delivered Pilates intervention significantly improves depression \& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS. Hypothesis Hypothesis 1: The 16-week remotely delivered Pilates intervention will significantly improve walking endurance, walking speed, balance, fatigue, and pain compared to a waitlist control group in individuals with MS. Hypothesis 2: Participants receiving the 16-week remotely delivered Pilates intervention will demonstrate significantly greater improvements in depression \& anxiety, cognitive function, and QOL compared to a waitlist control group in individuals with MS.
Detailed description
The current study will determine the feasibility and efficacy of a 16-week remotely delivered Pilates intervention for improving physical and psychological outcomes, and QOL, compared with a control condition, in individuals with MS. This represents a significant step forward in examining Pilates as an accessible, complementary therapy in MS.
Interventions
- Behavioral Pilates
REMOTLY PILATES EXERCISE
Primary outcome measures
- Change from baseline in walking endurance (Six-Minute Walk Test distance) [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in walking speed (Timed 25-Foot Walk) [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in balance (Berg Balance Scale) [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in fatigue (Fatigue Severity Scale) [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in pain (Short-form McGill Pain Questionnaire) [Time frame: Baseline and 16 weeks (end of treatment)]
Secondary outcome measures (6)
- Change from baseline in cognitive processing speed (Symbol Digit Modalities Test) [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in verbal learning and memory (California Verbal Learning Test-II) [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in visuospatial learning and memory (Brief Visuospatial Memory Test-Revised) [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in depression symptoms [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in anxiety symptoms [Time frame: Baseline and 16 weeks (end of treatment)]
- Change from baseline in health-related quality of life [Time frame: Baseline and 16 weeks (end of treatment)]
Eligibility criteria
Inclusion criteria
- Age 18 years or older
- Self-reported diagnosis of multiple sclerosis by a neurologist
- Relapse-free for the past 30 days before screening
- Able to speak and read English as the primary language
- Access to the internet and e-mail,
- Ability to use Zoom, and willingness to complete testing sessions and questionnaires
- Ambulatory without an assistive device (for example, cane)
- Low to moderate disability, defined as a score of 0-4 on the Patient-Determined Disease Steps (PDDS)
- Insufficiently active, defined as a score < 14 on the Godin Leisure-Time Exercise Questionnaire-Health Contribution Score (GLTEQ-HCS)
- Adequate visual ability and literacy to read materials printed in 14-point font
- Currently treated with a disease-modifying therapy
Exclusion criteria
- Pregnant
- Elevated risk for strenuous or maximal exercise, defined as more than one "Yes" response on the Physical Activity Readiness Questionnaire (PAR-Q) during screening
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Other
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07504120 · STUDY2025-0648-MOD001 · MB-2110-38597