Manual- VS Auto-Strain
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Transesophageal Echocardiography, Cardiac Anesthesia, Cardiac Surgery Patients. Basic parameters: 18 years — 99 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Austria
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Automated Measurements of Left Ventricular Longitudinal Strain: Are the Results Comparable to Manual Measurements During Cardiac Surgery?
Overview
Myocardial strain analysis provides additional and valuable information about left ventricular function, particularly in the perioperative setting with its dynamic changes in ventricular load conditions. This allows for earlier risk assessment and, if necessary, the initiation of faster and more targeted therapy. Unfortunately, conventional strain analysis using conventional methods currently takes approximately 5 minutes. However, this amount of time is often not available in a dynamically changing intraoperative setting during cardiac surgery. Therefore, the benefits of strain analysis have not yet been routinely utilized during the intraoperative course. However, new software solutions exist that can perform strain analysis fully automatically and reduce the examination time to a few seconds. However, it remains unclear whether these fully automated analyses also function reliably intraoperatively using transesophageal echocardiography (TEE). The aim of this study is to assess the reliability of these new methods.
Primary outcome measures
- Correlation between conventionally measured global longitudinal strain (GLS) and fully automated global longitudinal strain (Auto-GLS) [Time frame: 1-3 days]
Secondary outcome measures (1)
- Correlation between fully automated global longitudinal strain measured using GE EchoPac (GE-Auto-GLS) and fully automated global longitudinal strain measured using TOMTEC AutoStrain (TOMTEC Auto-GLS) [Time frame: 1 day]
Eligibility criteria
Inclusion criteria
- Adult (≥18 years) cardiac surgery patients
- Sinus rhythm
- No severe valvular regurgitation
- Use of General Electric (GE) echocardiography systems (Vivid S60, S70, E95) and corresponding EchoPAC software as well as TOMTEC software.
Exclusion criteria
- Inadequate image quality
- Any severe heart valve regurgitation
- Mechanical circulatory support systems (e.g., LVAD, Impella, ECMO)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Austria · 1 center
- General Hospital of Vienna - Medical University of Vienna — Vienna
Identifiers
NCT: NCT07496424 · MUV EK 2416/2025