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Not yet recruiting NCT07492186

3-hour Versus 12-hour Double-balloon Catheter for Labor Induction

No phase Interventional Induction of Childbirth

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Cook® double-balloon catheter.
Who it may be relevant to
Registry conditions: Induction of Childbirth. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Labor Induction With Double-balloon Catheter Placed for 3 Hours Versus 12 Hours in Patients With an Indication for Induction: a Randomized Controlled Trial

Overview

This study aims to demonstrate that a 3-hour ultra-short cervical ripening protocol using a double-balloon catheter significantly reduces the induction-to-birth interval by at least 6 hours compared to the standard 12-hour protocol. The study evaluates whether this reduction can be achieved without increasing cesarean section rates or maternal-fetal risks

Detailed description

Scientific Justification: Labor induction affects 25% of pregnancies in France, with 70% requiring cervical ripening. While the 12-hour pose is standard, recent evidence suggests that shorter durations (6h) are effective but remain difficult to integrate into hospital workflows. Since the mechanical and physiological effects of the balloon are early phenomena, a 3-hour protocol could optimize bed management and patient comfort.

Strategy: Comparison between an experimental group (3-hour balloon pose followed by immediate active labor management regardless of Bishop score) and a control group (standard 12-hour balloon pose).

Follow-up: Participants are followed from the day of induction until hospital discharge (generally 2 to 10 days) to assess obstetric outcomes, neonatal safety, and maternal satisfaction.

Interventions

  • Device Cook® double-balloon catheter
    For both arms, the same double-balloon device is used. After the allocated time (3h or 12h) or spontaneous expulsion, active labor management is initiated, including early amniotomy and/or oxytocin administration

Primary outcome measures

  • induction-to-birth interval reduction [Time frame: balloon insertion and birth of the child]

Eligibility criteria

Inclusion criteria

  • Age ≥ 18 years,
  • singleton pregnancy
  • ≥ 34 weeks of gestation,
  • cephalic presentation,
  • Bishop score < 6,
  • healthy uterus,
  • standard indication for labor induction

Exclusion criteria

  • Minor patients,
  • ruptured membranes,
  • twin pregnancy,
  • fetal malpresentation,
  • placenta previa,
  • previous uterine scar,
  • known fetal malformation

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Other

Study locations

France · 1 center
  • CH de Pau — Pau

Identifiers

NCT: NCT07492186 · CHPAU2026/01

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗