URINARY INCONTINENCE AND PELVIC FLOOR MUSCLE ACTIVITY IN MULTIPLE SCLEROSIS
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Multiple Sclerosis, Urinary Incontinence (UI). Basic parameters: 30 years — 50 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
FACTORS ASSOCIATED WITH URINARY INCONTINENCE AND EVALUATION OF PELVIC FLOOR MUSCLE ACTIVITY IN PATIENTS WITH MULTIPLE SCLEROSIS: CROSS-SECTIONAL STUDY
Overview
This study aims to investigate the relationship between urinary incontinence severity and surface electromyography (EMG) findings in women with multiple sclerosis. It will also examine the association of urinary incontinence with disability, quality of life, physical activity, and fatigue.
Detailed description
This study investigates the relationship between urinary incontinence (UI) severity and pelvic floor muscle activity in women with multiple sclerosis (MS). UI is common in MS and negatively affects quality of life, physical activity, and social participation. The study also explores how UI severity is associated with disability, fatigue, and overall quality of life.
Participants' demographic and clinical information, including age, disease duration, MS type, and disability level (measured by the Expanded Disability Status Scale, EDSS), will be recorded. Standardized questionnaires will assess urinary symptoms, their impact on daily life, physical activity, and fatigue. Pelvic floor muscle activity will be evaluated using surface electromyography (EMG) with biofeedback, conducted by trained physiotherapists.
The study will be conducted at the Pelvic Floor Health Center and is planned as a cross-sectional study. All assessments, including questionnaires and EMG measurements, are expected to take approximately 45 minutes per participant. Findings from this study aim to improve understanding of UI in women with MS and guide future interventions.
Primary outcome measures
- Pelvic floor muscle activity with surface EMG [Time frame: baseline]
Secondary outcome measures (4)
- International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) [Time frame: baseline]
- Incontinence Impact Questionnaire (IIQ-7) [Time frame: baseline]
- International Physical Activity Questionnaire (IPAQ) [Time frame: baseline]
- Fatigue Severity Scale (FSS) [Time frame: baseline]
Eligibility criteria
Inclusion criteria
Diagnosis of multiple sclerosis (MS) according to the 2017 revised McDonald criteria.
Female patients aged 30-50 years (age range with higher prevalence of urinary incontinence in MS).
Experiencing urinary incontinence (UI) symptoms according to the International Continence Society (ICS) definition.
EDSS (Expanded Disability Status Scale) score below 6.5.
Patients with no communication difficulties. -
Exclusion criteria
MS patients who do not provide consent to participate in the study.
MS patients who have had a medication change within the last 6 months.
Pregnant MS patients.
History of vaginal or cesarean delivery within the last 6 months.
Pelvic organ prolapse.
Urinary tract infection
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Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
Turkey (Türkiye) · 1 center
- Istanbul, Prof. Dr. Cemil Taşçıoğlu City Hospital, Turkey — Istanbul
Identifiers
NCT: NCT07489794 · MS-UI-PFM-2026