Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Lactated Ringer 500ml, Lactated Ringer 1000ml.
- Who it may be relevant to
- Registry conditions: Laparoscopic Cholecystectomy. Basic parameters: 18 years — 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Pakistan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effect of Liberal Versus Restrictive Intravenous Fluid Administration on Postoperative Homeostasis in Patients Undergoing Laparoscopic Cholecystectomy
Overview
The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability (homeostasis) among adults undergoing laparoscopic gallbladder removal (cholecystectomy). The main questions it aims to answer are: Does restrictive IV fluid administration maintain stable blood pressure, heart rate, and urine output after laparoscopic cholecystectomy? Are there any differences in postoperative recovery or complications between restrictive and liberal fluid regimens? Researchers will compare patients receiving liberal IV fluid administration with those receiving restrictive IV fluid administration to see if both methods maintain similar postoperative homeostasis and recovery outcomes. Participants will: Be adults aged 18-60 years (ASA class I-II) undergoing elective laparoscopic cholecystectomy. Be randomly assigned to one of two groups: Group A: Liberal IV fluid administration for 6 hours after surgery. Group B: Restrictive IV fluid administration for 6 hours after surgery. Have their vital signs (pulse, blood pressure, mean arterial pressure) and urine output recorded at multiple time points after surgery (immediate, 3, 6, 12, and 24 hours).
Interventions
- Drug Lactated Ringer 500ml
500ml ringer lactate perioperatively given in laparoscopic cholecystectomy patients as compared to traditional 1000ml fluid - Drug Lactated Ringer 1000ml
1000ml iv fluid given perioperatively in laparoscopic cholecystectomy
Primary outcome measures
- Mean Systolic Blood Pressure [Time frame: Day 1]
Secondary outcome measures (3)
- Mean Pulse Rate Per Minute [Time frame: Day 1]
- Mean Diastolic Blood Pressure [Time frame: Day 1]
- Mean Pulse Pressure [Time frame: Day 1]
Eligibility criteria
Inclusion criteria
- All patients undergoing elective cholecystectomy
- Age : 18-60 years
- All genders
- ASA class 1 and 2
Exclusion criteria
- History of previous laparotomy
- Perforated gall bladder
- Duration of surgery more than 3 hours
- More than 100ml intra operative blood loss
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Treatment
Study locations
Pakistan · 1 center
- King Edward Medical University Lahore / Mayo Hospital Lahore — Lahore
Identifiers
NCT: NCT07488078 · 335/RC/KEMU