LFP-based Parameter Prediction in DBS for Parkinson's Disease
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Parkinson's Disease (PD). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Belgium
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Assessing the Relation Between Subcortical LFPs and DBS Parameter Selection in Parkinson's Disease - a Prospective Study
Overview
The goal of this observational study is to assess whether deep brain stimulation (DBS) contact selection in Parkinson's disease could be informed by subcortical local field potential (LFP) recordings. The main question it aims to answer is: Aligns stimulation contact selection based on subcortical LFP recordings with clinically optimized contact selection? Participants will undergo LFP recordings that are part of standard clinical care during their routine hospital visits.
Primary outcome measures
- Alignment of contact selection [Time frame: From the first LFP recording to the last LFP recording (6 - 9 months)]
Eligibility criteria
Inclusion criteria
- Voluntary written informed consent of the participant
- At least 18 years of age at the time of signing the Informed Consent Form (ICF)
- Diagnosis of idiopathic Parkinson's disease according to the clinical diagnostic criteria of the Movement Disorder Society (MDS)
- Eligible for DBS to treat refractory PD motor symptoms, as based on multidisciplinary DBS screening
- Have sufficient understanding of the Dutch and French language to participate in the study
Exclusion criteria
- /
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Belgium · 1 center
- University Hospitals Leuven — Leuven
Identifiers
NCT: NCT07485621 · S71459