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Not yet recruiting NCT07485036

Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms

No phase Interventional Postpartum Depression (PPD) Alcohol Use Contingency Management Problem Solving Therapy

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Contingency Management & Problem Solving Therapy, Usual Care.
Who it may be relevant to
Registry conditions: Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms (MOMS-AD Pilot Study)

Overview

This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms. The main questions it seeks to answer are: 1. How do new mothers fare with depressive symptoms and alcohol use in the first 12 months after giving birth? 2. Will a CM-PST intervention reduce depressive symptoms and alcohol use frequency among new mothers? 3. Is a CM-PST intervention practical for new mothers? The researchers will recruit approximately 30 new mothers and randomly select half to attend a 6-week CM-PST intervention. They will compare those who received the intervention versus those who did not to see if there are any differences in their depressive symptoms and alcohol usage. Participants will: * Complete 4 remote intervention sessions over 6 weeks * Conduct at-home urine drug tests 2x per week during the 6-week intervention * Answer online surveys about their mental health and alcohol use

Interventions

  • Behavioral Contingency Management & Problem Solving Therapy
    A 6-week online CM-PST course delivered through video conferencing calls consisting of 4 educational sessions, combined with 2x weekly at-home drug testing to monitor the reduction in alcohol use and reduced depression symptoms.
  • Other Usual Care
    Participants randomized to the usual care condition will continue to receive standard postpartum care from their obstetrician-gynecologist, consistent with routine clinical practice. No additional psychological intervention will be provided as part of the study.

Primary outcome measures

  • Change in postpartum depression symptoms [Time frame: Screening, Baseline, 3 months]
  • Alcohol use test results [Time frame: Baseline, Weekly, 3 months]
  • Change in alcohol use screening status [Time frame: Screening, Baseline, 3 months]
  • Change in alcohol-related negative consequences [Time frame: Baseline, 3 months]
  • Change in alcohol use [Time frame: Baseline, 3 months]
  • Change in reasons for drinking [Time frame: Baseline, 3 months]
Secondary outcome measures (3)
  • Acceptability of intervention [Time frame: 3 months]
  • Feasibility of intervention via adherence [Time frame: 3 months]
  • Feasibility of intervention via retention [Time frame: 3 months]

Eligibility criteria

Inclusion criteria

  • Biologically female
  • Age ≥18 years
  • Within 12 months postpartum
  • Able to provide informed consent

Exclusion criteria

  • Serious medical or psychiatric conditions requiring hospitalization
  • Lifetime DSM-5 diagnosis of schizophrenia, bipolar disorder, or any psychiatric disorder
  • Current use of psychoactive drugs, medication to treat problematic alcohol use, or depression
  • Participation in past 6 months in problematic alcohol use or substance use treatment
  • Unable to provide consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

United States · 1 center
  • University of Illinois Hospital and Health Sciences System, University of Illinois College — Chicago

Identifiers

NCT: NCT07485036 · 2026-0112

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗