Image Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Ultrasound Guided, Fluoroscope Guided.
- Who it may be relevant to
- Registry conditions: Chronic Knee Osteoarthritis. Basic parameters: from 50 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Efficacy of Ultrasound vs Fluoroscopy Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis: A Randomized Controlled Trial
Overview
The goal of this prospective randomized control trial is to provide continued pain relief, classically long-lasting 3 to12 months, and enhanced function in patients following: both gender; male and female, age group; \>50yr, healthy volunteers along with Radiographic diagnosis of knee OA with KL grade 3 and 4 in addition of Chronic knee pain ≥ 6 months and patients with ≥50% decrease in pain strength after diagnostic genicular nerve block. The main question it aims to answer is: Is ultrasound-guided genicular nerve RFA more efficient in lowering pain intensity at six months contrasted with fluoroscopic guided method in patients with chronic knee osteoarthritis? Researchers will compare Group A (Fluoroscopic) to Group B (Ultrasound) to see comparison in efficiency of ultrasound guided against fluoroscopic guided genicular nerves block for decrease in pain intensity and functional improvement.
Interventions
- Procedure Ultrasound Guided
Genicular nerves radiofrequency ablation will be done with the help of ultrasound guidance. - Procedure Fluoroscope Guided
Control group in which genicular nerves radiofrequency ablation will be done with the help of fluoroscopic guidance.
Primary outcome measures
- Effectiveness of Block [Time frame: Post procedure 2 weeks, then follow up after 2, 4 and 6 months.]
Secondary outcome measures (1)
- Functional Improvement after block [Time frame: 6 months]
Eligibility criteria
Inclusion criteria
- Both gender patients of age more than 50 years.
- Radiographic diagnosis of knee OA with KL level 3 and 4.
- Chronic knee pain for more than 6 months
- Patients with more than 50% reduction in pain intensity after diagnostic genicular nerve block
Exclusion criteria
- Lack of consent
- surgery of knee
- Patient with BMI more than 40kg/m2
- Intra-articular steroid injection or hyaluronic acid in last 3 months
- Localized infection at procedure site or knee.
- Patient unable to communicate properly (Severe psychiatric illness, severe dementia and cognitive impairment).
- Patients have moderate to severe low back pain (NRS ≥5)
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07475793 · 2026-12711-40401