Menu
Not yet recruiting NCT07473882

Intraventricular Hemorrhage in Kangaroo Care vs. Incubator Care

No phase Interventional Kangaroo Care Premature Infant IVH- Intraventricular Hemorrhage

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Lateral, Prone, Incubator care.
Who it may be relevant to
Registry conditions: Kangaroo Care, Premature Infant, IVH- Intraventricular Hemorrhage. Basic parameters: 1 Minute — 72 Hours · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Spain
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Kangaroo Care in Extremely Preterm Newborns Versus Incubator Care and Intraventricular Hemorrhage: A Multicenter RCT

Overview

This clinical study aims to find out whether kangaroo care (skin-to-skin contact between parents and their extremely premature newborns) can help protect the babies' brains by reducing the risk of bleeding in the brain during the first days of life. To do this, the extremely premature newborns will be randomly assigned to one of three groups: kangaroo care in a side-lying position, kangaroo care in a face-down position, or standard care in an incubator. Researchers will monitor the babies for signs of brain bleeding and other health measures to determine which approach is safest. The main hypothesis is that kangaroo care in the side-lying position may lower the risk of severe brain bleeding compared with the other positions or remaining in the incubator.

Detailed description

This protocol describes a multicenter, randomized, parallel-group clinical trial designed to evaluate the safety and effects of early kangaroo care on cerebral stability in extremely preterm newborns during the first 72 hours of life. Participants will be randomly assigned to one of three postural management strategies: side-lying kangaroo care, prone kangaroo care, or conventional incubator care. The study includes standardized implementation of the intervention across centers, serial clinical and neurological monitoring, as well as brain imaging and noninvasive cerebral oxygenation monitoring to assess the physiological effects associated with each position. Analyses will follow the intention-to-treat principle, comparing safety and clinical outcomes between groups while adjusting for relevant perinatal factors. The design incorporates quality control procedures, staff training, blinded image assessment, and ethical and regulatory safeguards to ensure methodological rigor and patient protection.

Interventions

  • Procedure Lateral
    lateral Kangaroo care position: The preterm infant will be placed unclothed against the parent's chest in a side-lying position, aligned along the midline.
  • Procedure Prone
    prone kangaroo care position: The preterm infant will be positioned prone against the parent's chest, upright, with the head turned 90° to one side.
  • Procedure Incubator care
    Kangaroo care will not be provided during the first three days of life, and the infant will remain in the incubator.

Primary outcome measures

  • Severe Intraventricular hemorrhage [Time frame: HIV appearance: from before 6 hours of life to at least 7 days of life]

Eligibility criteria

Inclusion criteria

  • Preterm infants born at 28 weeks of gestational age or less, admitted to the NICU and born at the study center (inborn), less than 72 hours old, with a parent or legal guardian present who is willing to provide kangaroo care.

Exclusion criteria

  • Preterm infants in the immediate postoperative period following major surgery.
  • Preterm infants with congenital abdominal wall malformations.
  • Preterm infants requiring immobilization.
  • Preterm infants who are clinically unstable and unable to tolerate kangaroo care.
  • Preterm infants whose parents decline participation in the study.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

Spain · 1 center
  • Hospital Universitario 12 de Octubre — Madrid

Identifiers

NCT: NCT07473882 · KANVIH_25/711 · PI25/01534

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗