Indicators Affecting PVT Recanalization
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Portal Vein Thrombosis, Cirrhosis, Portal Hypertension Related to Cirrhosis, Portal Hypertension, Noncirrhotic. Basic parameters: 18 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Indicators Affecting Portal Vein Thrombosis Recanalization in Cirrhosis With Gastroesophageal Varices
Overview
This is a retrospective-prospective study conducted at Zhongshan Hospital, Fudan University, to explore portal vein thrombosis (PVT) in patients with cirrhosis and gastroesophageal varices (GEV). It aimed to provide insights into the diagnosis, follow-up, and factors influencing PVT recanalization, to help patients, families, and healthcare providers understand the disease and related clinical management.
Primary outcome measures
- PVT recanalization at 1 year [Time frame: From the first abdominal imaging assessment after admission, until the occurrence of PVT recanalization at 1 year, death, or the last follow-up, whichever came first]
Secondary outcome measures (3)
- Occurrence of all-cause death (competing event) [Time frame: From the date of admission confirmation of PVT to the occurrence of death, or the last follow-up, whichever came first]
- PVT recanalization at 5 years [Time frame: From the first abdominal imaging assessment after admission, until the occurrence of PVT recanalization at 5 year, death, or the last follow-up, whichever came first]
- Occurrence of non-improved PVT [Time frame: From the date of admission confirmation of PVT to the last radiological follow-up at 1 year, or death, whichever came first]
Eligibility criteria
Inclusion criteria
- diagnosed as cirrhosis and confirmed gastroesophageal varices by endoscopy;
- all patients were diagnosed as PVT by CTA at admission.
Exclusion criteria
- patients with hepatocellular carcinoma;
- patients with extrahepatic malignancies;
- history of liver transplantation or TIPS;
- lack of information regarding anticoagulation therapy；
- those with cavernous transformation of the portal vein(CTPV) .
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Center not named — Shanghai
Identifiers
NCT: NCT07473375 · CSY-PVT-anticoagulation