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Recruiting NCT07472010

Mandibular Stretching and 4-4-8 Breathing Exercises on Autonomic Nervous System Activity

No phase Interventional Muscle Tone Psychological State Autonomic Nervous System

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Mandibular Stretching Exercise, 4-4-8 Breathing Exercise.
Who it may be relevant to
Registry conditions: Muscle Tone, Psychological State, Autonomic Nervous System. Basic parameters: 18 years — 30 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Investigation of the Effects of Mandibular Stretching Exercise and 4-4-8 Breathing Exercise on Autonomic Nervous System Activity, Muscle Tone, and Psychological State: A Randomized Controlled Trial

Overview

Mandibular stretching exercises and breathing techniques may influence autonomic nervous system activity, muscle tone, and psychological state. This randomized controlled trial aims to investigate the effects of mandibular stretching exercise and the 4-4-8 breathing exercise on autonomic nervous system activity, muscle tone, and psychological parameters in healthy university students. Participants will be randomly assigned to intervention groups and evaluated before and after the intervention period.

Detailed description

The autonomic nervous system plays an important role in regulating physiological and psychological responses. Breathing techniques and mandibular stretching exercises are non-invasive approaches that may influence autonomic nervous system activity and muscle tone through neuromuscular and respiratory mechanisms. However, the combined or individual effects of these interventions on autonomic regulation and psychological outcomes remain insufficiently investigated.

This randomized controlled trial aims to examine the effects of mandibular stretching exercise and the 4-4-8 breathing exercise on autonomic nervous system activity, muscle tone, and psychological state in healthy university students. Participants will be randomly allocated to intervention groups according to the study protocol. Baseline and post-intervention measurements will be collected to evaluate changes in autonomic nervous system parameters, muscle tone, and psychological status.

The findings of this study may contribute to understanding the potential benefits of simple non-pharmacological interventions such as mandibular stretching and breathing exercises in improving physiological regulation and psychological well-being.

Interventions

  • Other Mandibular Stretching Exercise
    Participants perform mandibular stretching exercises according to the study protocol
  • Other 4-4-8 Breathing Exercise
    Participants perform the 4-4-8 breathing exercise according to the study protocol.

Primary outcome measures

  • Autonomic Nervous System Activity [Time frame: Baseline and 20, 40, 80, and 120 minutes after the intervention]
Secondary outcome measures (2)
  • Muscle Tone [Time frame: Baseline and 20, 40, 80, and 120 minutes after the intervention]
  • Psychological State [Time frame: Baseline and 20, 40, 80, and 120 minutes after the intervention]

Eligibility criteria

Inclusion criteria

  • Inclusion Criteria:
  • Healthy university students
  • Age between 18 and 30 years
  • Voluntary participation in the study
  • Ability to understand and perform mandibular stretching exercise and 4-4-8 breathing exercise

Exclusion criteria

  • History of neurological disorders
  • Musculoskeletal disorders affecting the jaw, neck, or respiratory system
  • Respiratory diseases
  • Use of medications that may affect the autonomic nervous system
  • Inability to perform the exercises required in the study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Turkey (Türkiye) · 1 center
  • Necmettin Erbakan University — Konya

Identifiers

NCT: NCT07472010 · NEU-2025-THESIS01

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗