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Recruiting NCT07468734

Shock Wave Versus Traditional Physical Therapy for Adult Chronic Knee Osteoarthritis

No phase Interventional Shock Wave Traditional Physical Therapy Chronic Knee Osteoarthritis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Extracorporeal shock wave therapy, Exercise therapy program.
Who it may be relevant to
Registry conditions: Shock Wave, Traditional Physical Therapy, Chronic Knee Osteoarthritis. Basic parameters: from 40 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Shock Wave Versus Traditional Physical Therapy for Adult Chronic Knee Osteoarthritis: A Prospective Randomized Controlled Trial

Overview

This study aims to compare the effectiveness of extracorporeal shock wave therapy (ESWT) versus structured therapeutic exercise in patients with chronic knee osteoarthritis (KOA), with respect to pain reduction and improvement of knee function.

Detailed description

Knee osteoarthritis (KOA) is a highly prevalent chronic degenerative joint disease characterized by progressive cartilage loss, chronic pain, stiffness, functional disability, and reduced quality of life in adults, particularly the elderly.

Extracorporeal shock wave therapy (ESWT) has emerged as a non-invasive physical modality that delivers acoustic pressure waves to musculoskeletal tissues, stimulating biological responses such as enhanced microcirculation, anti-inflammatory cytokine modulation, neovascularization, cartilage and bone repair processes, and decreased pain transmission.

Interventions

  • Other Extracorporeal shock wave therapy
    Patients will receive extracorporeal shock wave therapy.
  • Other Exercise therapy program
    Patients will undergo a structured exercise therapy program.

Primary outcome measures

  • Change in pain intensity [Time frame: 5-week after intervention]
Secondary outcome measures (4)
  • Stiffness assessment [Time frame: 5-week after intervention]
  • Assessment of physical function [Time frame: 5-week after intervention]
  • Knee range of motion [Time frame: 5-week after intervention]
  • Incidence of adverse events [Time frame: 5-week after intervention]

Eligibility criteria

Inclusion criteria

  • Adults ≥ 40 years with clinical and radiographic diagnosis of chronic knee osteoarthritis (KOA) (Kellgren-Lawrence grade II-III).
  • Both sexes.
  • Persistent knee pain ≥ 3 months.
  • Ability to provide consent and participate in interventions.

Exclusion criteria

  • Prior knee surgery within last 6 months.
  • Intra-articular injections in the last 3 months.
  • Systemic inflammatory arthritis or other neurological conditions affecting gait.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • German International University — Cairo

Identifiers

NCT: NCT07468734 · DCSR-02026-104

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗