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Not yet recruiting NCT07467941

Impact of Visceral Adiposity on Postoperative Atrial Fibrillation After CABG

— Observational CABG Visceral Adipose Tissue Atrial Fibrillation (AF)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Postoperative AF Group, Non-AF Group.
Who it may be relevant to
Registry conditions: CABG, Visceral Adipose Tissue, Atrial Fibrillation (AF). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Impact of Visceral Adiposity on Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG): A Prospective Observational Study

Overview

Obesity has become a major public health problem in both developed and developing countries, with a continuous increase particularly since the 1980s. Moreover, it is a well-established metabolic risk factor for diabetes mellitus, hypertension, and various types of cancer, as well as cardiovascular diseases such as heart failure and coronary artery disease. Body mass index (BMI) is calculated by dividing body weight in kilograms by the square of height in meters and is widely used as an indicator of obesity. However, BMI does not quantitatively reflect body fat distribution and fails to account for components such as skeletal muscle and bone mass. Therefore, interest in assessing body fat distribution has increased, and in recent years, studies evaluating the correlation between anthropometric, biochemical, and anatomical measurements and clinical outcomes have become more frequent. In particular, it is acknowledged that abdominal obesity cannot be accurately represented by BMI alone and is primarily associated with visceral adipose tissue (VAT). The aim of this study is to evaluate the association between preoperative visceral and subcutaneous adipose tissue measurements (VAT and SAT), assessed by ultrasonography in patients scheduled for open-heart surgery, and the development of postoperative atrial fibrillation.

Interventions

  • Other Postoperative AF Group
    In patients undergoing coronary artery bypass graft surgery, ultrasound-guided measurements of visceral and subcutaneous adipose tissue will be performed preoperatively. The relationship between adipose tissue thickness and the development of postoperative atrial fibrillation will be evaluated by comparing patients who develop AF with those who do not.
  • Other Non-AF Group
    In patients undergoing coronary artery bypass graft surgery, ultrasound-guided measurements of visceral and subcutaneous adipose tissue will be performed preoperatively. The relationship between adipose tissue thickness and the development of postoperative atrial fibrillation will be evaluated by comparing patients who develop AF with those who do not.

Primary outcome measures

  • Effect of visceral adipose tissue thickness on postoperative atrial fibrillation [Time frame: Within 7 days after coronary artery bypass graft surgery or until hospital discharge]

Eligibility criteria

Inclusion criteria

  • Elective isolated coronary artery bypass graft surgery (on-pump)
  • Age ≥18 years, planned prospectively in 300 patients

Exclusion criteria

  • Patients requiring urgent or emergency surgery
  • Off-pump coronary artery bypass graft surgery
  • Surgeries other than isolated coronary artery bypass graft
  • Patients in whom abdominal ultrasound measurement cannot be performed (e.g., due to severe deformity, wounds, edema)
  • Active malignancy
  • eGFR <30 mL/min
  • Advanced-stage chronic obstructive pulmonary disease (COPD)
  • Preoperative atrial fibrillation or atrial flutter
  • Patients who do not provide written informed consent for the study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Other

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07467941 · 2025/23/1318

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗