The Rapid Shallow Breathing Index (RSBI) is a Widely Used Predictor for Weaning Patients From Mechanical Ventilation This Study Aims to Determine the Predictive Value of RSBI Measurements for Extubation Success in Mechanically Ventilated ICU Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Ventilated Patient in Intensive Care, Failure of Extubation. Basic parameters: from 22 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Rapid Shallow Index as Successfully Predictor of Outcome of Extubating
Overview
Early extubation in ICU patients is crucial for reducing complications of prolonged ventilation, including morbidity and mortality. The Rapid Shallow Breathing Index (RSBI) is a widely used predictor for weaning patients from mechanical ventilation. This study aims to determine the predictive value of RSBI measurements for extubation success in mechanically ventilated ICU patients
Detailed description
The extubation decision is a combined clinical judgment based on a passing Spontaneous Breathing Trial (SBT) and a Rapid Shallow Breathing Index (RSBI) value ≤ 105 breaths/min/L.combination of criteria (SBT + RSBI threshold) This approach is recommended to improve predictive accuracy, as neither SBT nor RSBI alone is perfectly reliable.
Primary outcome measures
- Extubation success (no reintubation/adjuvant support within 48h). [Time frame: 48 hour]
Eligibility criteria
Inclusion criteria
- • Adults > 22 years.
- Mechanically ventilated patients meeting extubation readiness:
- FiO₂ ≤ 0.4, PEEP ≤ 8 cmH₂O, PaO₂/FiO₂ ≥ 200 mmHg.
- Respiratory rate ≤ 35 breaths/min, pH > 7.30.
- Hemodynamic stability (HR ≤ 120 bpm, SBP 90-160 mmHg).
- Glasgow Coma Scale >10, adequate cough reflex.
- Includes postoperative, elective/emergency reintubation, and tracheostomized patients.
Exclusion criteria
- Age <22 years.
- Refusal of informed consent.
- Altered mental status (e.g., traumatic brain injury).
- Hemodynamic instability or deep sedation (RASS ≤ -2).
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Egypt · 1 center
- Ain Shams Hospital — Cairo
Identifiers
NCT: NCT07467265 · FAMSU R39/2026