Establishment of Image Database for Early Upper Gastrointestinal Cancer, Precancerous Lesions, and Precancerous Conditions
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: magnetically-controlled capsule endoscopy, esophagogastroduodenoscopy, CT scan, ESD, biopsy.
- Who it may be relevant to
- Registry conditions: Upper Gastrointestinal Cancer, Upper Gastrointestinal Precancerous Lesions, Upper Gastrointestinal Precancerous Conditions. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The study is designed to collect magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, CT images, and histopathology results to establish a database for early upper gastrointestinal cancer, precancerous lesions, and precancerous conditions.
Detailed description
Images of MCE for UGIC are scarce, limiting the development of corresponding AI diagnostic model. We aim to create an image database with MCE images, EGD images, CT images, and histopathology results, in patients treated by ESD for early upper gastrointestinal cancer, or biopsy for precancerous lesions, and precancerous conditions, so as to facilitate image-based deep learning studies.
Interventions
- Diagnostic test magnetically-controlled capsule endoscopy, esophagogastroduodenoscopy, CT scan
Magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, and CT images for early upper gastrointestinal cancer, precancerous lesions, and precancerous conditions - Procedure ESD, biopsy
ESD or biopsy for histopathology results
Primary outcome measures
- Magnetically-controlled capsule endoscopy (MCE) images, esophagogastroduodenoscopy (EGD) images, and CT images [Time frame: Prior to ESD or biopsy]
- Histopathology results [Time frame: During ESD or biopsy]
Eligibility criteria
Inclusion criteria
- Male or female participants aged ≥ 18 years
- Patients with early upper gastrointestinal cancer referred for endoscopic submucosal dissection (ESD), or patients with upper gastrointestinal precancerous lesions or precancerous conditions referred for biopsy by esophagogastroduodenoscopy (EGD)
- Participants who are willing and able to participate in this study, complete all required examinations and follow-up visits, and who have provided written informed consent
Exclusion criteria
- Patients who are not eligible for surgery or who refuse any abdominal surgery in case of capsule retention and endoscopic retrieval failure
- Patients with cardiac pacemaker or other implanted electromedical devices which could interfere with magnetic resonance
- Suspected or known intestinal stenosis or other known risk factors for capsule retention
- Patients with dysphagia
- Pregnancy
- Allergy to polymeric materials, latex, simethicone, or pronase
- Patients plan to undergo magnetic resonance imaging examination before excretion of the capsule
- Patients with any condition that precludes compliance with the study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Changhai Hosptial — Shanghai
Identifiers
NCT: NCT07462247 · CHEC2026-069