Mesenteric Ischemia Markers Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Blood samples.
- Who it may be relevant to
- Registry conditions: Mesenteric Vascular Disease. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Belarus
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Mesenteric Ischemia Markers Study In The Presence Of Mesenteric Arteries Disease
Overview
Vascular bowel disease remains a socially significant and potentially fatal condition (if it develops into AMI), primarily due to delayed diagnosis. Blood biomarkers are theoretically ideal for early risk stratification (like troponins in myocardial infarction). However, the existing evidence base is characterized by low quality and high heterogeneity, which hinders their use in clinical practice. Therefore, there is an urgent and unmet clinical need for high-quality, methodologically rigorous research to validate biomarkers in MI. A current study (MESMARK) is to be undertaken to identify combinations of biomarkers that can reliably identify mesenteric ischemia (MI) and distinguish between non-transmural and transmural clinical relevant ischemia.
Interventions
- Diagnostic test Blood samples
Blood samples as diagnostic tests are the only intervention in the trial
Primary outcome measures
- Increasing in the level of mesenteric ischemia (MI) markers above the reference threshold level within 1 day after enrollment in the study [Time frame: From enrollment to the 24 hours]
Eligibility criteria
Inclusion criteria
- 18 years or older, all sex
- Initial decision, the presence of angio-visualisation of the MA and suspicion of mesenteric arteries diseases
- Patient's consent to participate in the study
- No pregnancy, no history of major operations on MA, the gastrointestinal tract and digestive organs (except appendectomy, endoscopic polypectomy).
Exclusion criteria
- Consent declined by patient or relatives
- Failure to meet inclusion criteria
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Diagnostic
Study locations
Belarus · 1 center
- Belarusian State Medical University — Minsk
Identifiers
NCT: NCT07460700 · 35-20240303-2026