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Enrolling by invitation NCT07456137

Prospective Evaluation of Upright Versus Supine CT Myelography of the Lumbar Spine

No phase Interventional Lumbar Central Canal Stenoses Neural Foraminal Stenoses

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Upright CT.
Who it may be relevant to
Registry conditions: Lumbar Central Canal Stenoses, Neural Foraminal Stenoses. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The purpose of this prospective study is to compare the diagnostic utility of standing (upright, weight-bearing) CT myelography with standard supine CT myelography for the evaluation of lumbar central canal and neural foraminal stenoses. This study aims to determine whether upright positioning provides additional diagnostic information in patients unable to undergo MRI, with the goal of improving assessment and management of degenerative lumbar spine disease.

Interventions

  • Radiation Upright CT
    Upright CT Myelography

Primary outcome measures

  • Does upright CT imaging change management plans for patients with lumbar spinal stenosis [Time frame: 1 week]
Secondary outcome measures (6)
  • Spine measurements [Time frame: 1 day]
  • Severity grading of central canal stenosis [Time frame: 1 day]
  • Severity grading of neural foraminal stenosis [Time frame: 1 day]
  • Presence or absence of nerve root compression [Time frame: 1 day]
  • Presence or absence of disc bulges [Time frame: 1 day]
  • Presence or absence of herniations [Time frame: 1 day]

Eligibility criteria

Inclusion criteria

  • Age ≥ 18 years
  • Outpatient status
  • Scheduled for routine supine CT myelography

Exclusion criteria

  • Inpatient status
  • Presence of metallic lumbar spinal hardware
  • History of osseous metastatic disease involving the lumbar spine
  • Acute traumatic injury involving the lumbar spine
  • Pregnancy
  • Participant body habitus exceeding the scanner's safe operational limits (e.g., gantry/bore size clearance, table weight capacity) as defined by the device manufacturer.
  • Inability to tolerate CT scanning (e.g., severe pain, unable to stand independently for an extended period)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Treatment

Study locations

United States · 1 center
  • The University of Kansas Medical Center — Kansas City

Identifiers

NCT: NCT07456137 · STUDY00162088

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗