Chronic Total Occlusion and Triglyceride-Glucose Index
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2..
- Who it may be relevant to
- Registry conditions: CAD - Coronary Artery Disease, Chronic Total Occlusion (CTO), Triglycerid Glucose Index. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Role of the Triglyceride-Glucose Index in Determining the Risk of Chronic Total Occlusion in Coronary Artery Disease
Overview
We retrospectively analyzed 200 CAD patients undergoing coronary angiography between 2026-2027. Patients were grouped by CTO presence. Clinical and laboratory parameters were compared, and logistic regression was performed to identify independent predictors.
Interventions
- Diagnostic test triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2.
As no previous studies have demonstrated the predictive value of the TyG index for chronic total occlusion (CTO), the present investigation provides a novel contribution to the literature. We hypothesize that the triglyceride-glucose (TyG) index will be significantly higher in patients with chronic total occlusion (CTO) compared to those without CTO.
Primary outcome measures
- The primary outcome measure will be the difference in the triglyceride-glucose (TyG) index between patients with chronic total occlusion (CTO) and those without CTO, assessed from routinely obtained blood samples. [Time frame: 1 Year]
Eligibility criteria
Inclusion criteria
- Adults ≥18 years of age, patients undergoing coronary angiography, non-obese individuals
Exclusion criteria
- Patients <18 years of age, history of atrial fibrillation, pacemaker implantation, asthma, pulmonary hypertension, pregnancy, anemia, malignancy, rheumatoid arthritis, or peripheral artery disease, obesity (BMI >30 kg/m²), inaccessible patient records
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 1 center
- Kırıkkale university — Kirikkale
Identifiers
NCT: NCT07451860 · 2026.02.17