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Recruiting NCT07449806

Assessment of Labial Plate Thickness After Immediate Implant Placement Using Two Different Xenografts in the Esthetic Zone

No phase Interventional Alveolar Bone Loss Tooth Extraction Status Nos Immediate Implant Placement

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Immediate Implant Placement with Medpark S1 xenograft, Immediate Implant Placement with bio-Oss xenograft.
Who it may be relevant to
Registry conditions: Alveolar Bone Loss, Tooth Extraction Status Nos, Immediate Implant Placement. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Assessment of Labial Plate Thickness After Immediate Implant Placement in Type II Extraction Sockets Using Two Different Xenografts in the Esthetic Zone: a Randomized Controlled Clinical Trial

Overview

This randomized clinical trial aims to evaluate labial bone plate changes following immediate implant placement in Type II extraction sockets using two different xenograft materials and de-epithelialized free gingival graft in the esthetic zone . Patients requiring extraction and immediate implant placement will be randomly allocated into two groups according to the xenograft material used for defect grafting. Clinical and radiographic outcomes will be assessed to determine dimensional bone changes and implant success

Detailed description

Immediate implant placement in the esthetic zone has become a predictable treatment modality aiming to reduce treatment time while preserving alveolar bone and soft tissue architecture. However, dimensional alterations of the labial bone plate remain a clinical concern, particularly in Type II extraction sockets.

The present randomized controlled clinical trial will compare the effect of two different xenograft materials and de-epithelialized free gingival graft used for defect grafting during immediate implant placement. Eligible patients indicated for tooth extraction and immediate implant placement will be randomly assigned into two parallel groups based on the grafting material used.

Clinical evaluation and standardized radiographic assessment using CBCT will be performed to measure labial plate thickness changes, peri-implant bone stability, and implant success outcomes over a defined follow-up period. The findings of this study aim to provide clinical evidence regarding the most effective xenograft material for preserving peri-implant hard tissue contours in the esthetic zone

Interventions

  • Procedure Immediate Implant Placement with Medpark S1 xenograft
    Immediate implant placement in Type II extraction sockets, with gap grafting using Medpark S1 xenograft .
  • Procedure Immediate Implant Placement with bio-Oss xenograft
    Immediate implant placement in Type II extraction sockets, with gap grafting using bio-Oss xenograft

Primary outcome measures

  • Labial Bone Plate Thickness Change [Time frame: 6 months post-implant placement]
Secondary outcome measures (1)
  • Peri-implant mucosal level (PML) [Time frame: 6 months post-implant placement]

Eligibility criteria

Inclusion criteria

  • Patients with one or more non-restorable teeth or remaining roots without signs of acute infection in the maxillary anterior region.
  • Type II extraction sockets.
  • Sufficient bone (>3 mm) apically and palatally to allow for proper implant positioning with sufficient primary stability (≥ 30 N cm).
  • Good compliance.

Exclusion criteria

  • Teeth with current acute periapical infection.
  • Medically compromised patients.
  • Heavy smokers (smoking of more than 10 cigarettes per day ).
  • Alcohol or drug abuse.
  • Patients undergoing chemotherapy and radiotherapy.
  • Poor oral hygiene.
  • Vulnerable groups (pregnant females and decision- impaired individual).

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Faculty of Dentistry, Alexandria University, Egypt — Alexandria

Identifiers

NCT: NCT07449806 · 1077-05/2025

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗