Investigating the Effects of Cognitive Functional Therapy on Pain, Physical Function, and Kinesiophobia in Individuals With Chronic Ankle Sprain
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Cognitive Functional Therapy.
- Who it may be relevant to
- Registry conditions: Chronic Ankle Sprain, Chronic Ankle Sprains. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The aim of this study is to investigate the effects of Cognitive Functional Therapy (CFT) on pain, physical function, and kinesiophobia in individuals with chronic ankle sprain (CAS).
Detailed description
The aim of this study is to investigate the effects of Cognitive Functional Therapy (CFT) on pain, physical function, and kinesiophobia in individuals with chronic ankle sprain (CAS). This study will follow a structured clinical research protocol designed to evaluate the effects of Cognitive Functional Therapy (CFT) on individuals with chronic ankle sprain.
This study is an experimental clinical intervention with a two-time-point measurement design. The Cognitive Functional Therapy (CFT) program will be applied to individuals with chronic ankle sprain, and its effects will be evaluated at baseline (before intervention) and after the 12-week intervention.
The study will take place between January 2026 and June 2026. All participants will undergo an initial eligibility screening by an orthopedic specialist prior to enrollment. Following informed consent, eligible participants will attend a baseline assessment session, complete validated self-report questionnaires, and then begin a 12-week individualized CFT program consisting of seven sessions. Interventions will be delivered by a trained physiotherapist with clinical experience in musculoskeletal rehabilitation and certification in CFT principles. All data collection, including digital files and paper records, will be securely stored in encrypted systems accessible only to the research team. At the conclusion of the 12-week program, participants will fill the same questionnaires they filled at the beginning of the study as an outcome measurement.
The outcome measurements are VAS, TSK-17, and FAAM questionnaires.
Interventions
- Procedure Cognitive Functional Therapy
Cognitive Functional Therapy is an integrated behavioral approach for individualizing the management of people with chronic pain, originally developed for Low Back Pain Patients. It uses a multidimensional "clinical reasoning framework" to identify key modifiable targets for management on the basis of careful listening to the individual's story and examining the individual's behavioral responses to pain. This approach enables the treating clinician to take individuals on a journey to effectively
Primary outcome measures
- FAAM [Time frame: 12 Weeks]
- TSK-17 [Time frame: 12 Weeks]
- VAS [Time frame: 12 Weeks]
Eligibility criteria
Inclusion criteria
- Ongoing pain or swelling, "giving way" episodes, and re-injury during sports or daily activity
- Adults aged 18-65 years
- History of lateral ankle sprain with symptoms persisting for more than 3 months
- Continuing symptoms such as pain, instability, or activity limitations
- Ability to understand and communicate in English or Arabic
Exclusion criteria
- History of ankle surgery within the past 12 months
- Advanced ankle osteoarthritis or systemic inflammatory, neurological, or vestibular conditions
- Currently undergoing physiotherapy for the same condition
- Cognitive impairment or severe psychological disorder that could interfere with participation
- Pregnancy or planned pregnancy during the study period
- Any other condition deemed unsuitable by the research team
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Turkey (Türkiye) · 1 center
- Yeditepe University — Istanbul
Identifiers
NCT: NCT07449078 · Abdullah Omar A, PT