Adjunctive Diode Laser Therapy in Non-Surgical Periodontal Therapy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: LASER assisted SRP, RsD.
- Who it may be relevant to
- Registry conditions: Periodontal Disease, Periodontal Pockets, Periodontal Attachment Loss. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Israel
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Evaluation of the Effect of Adjunctive Diode Laser Therapy in Mechanical Scaling and Root Surface Debridement in Non-Surgical Periodontal Therapy
Overview
The goal of this clinical trial is to evaluate the efficacy of adjunctive application of diode laser to mechanical, non-surgical root surface debridement in patients attending periodontal office. The main question it aims to answer is: To compare the clinical effectiveness of adjunctive application of a 940-nm diode laser with root surface debridement to the effectiveness of root surface debridement alone. This study is a split-mouth design, where each quadrant will be randomly allocated to one of the following groups: Control group (root surface debridement - RsD): scaling and root planing alone. Laser group (RsD + laser): scaling and root planing with adjunctive diode laser therapy Quadrants will be randomly allocated to the treatment groups
Interventions
- Device LASER assisted SRP
Two quadrants will be treated mechanically (ScR) with adjunctive diode laser and another two quadrants mechanically (ScR) only - Device RsD
mechanical root surface debridement with periodontal curettes
Primary outcome measures
- PPD [Time frame: prior to treatment and 12 weeks and 6 months after treatment]
Secondary outcome measures (2)
- CAL [Time frame: prior to treatment and 12 weeks and 6 months after the treatment]
- BOP [Time frame: prior to treatment and 12 weeks and 6 months after the treatment]
Eligibility criteria
Inclusion criteria
- Systemically healthy patients
- Each patient should have more than 20 teeth remaining, and at least 5 teeth per quadrant
- Each patient presented ≥ 30% of sites involved
- At least 2 teeth with a probing depth of ≥ 5 mm in each quadrant, with evident radiographic bone loss.
Exclusion criteria
- History of systemic diseases affecting the periodontium
- Smokers and alcoholic patients
- Use of medication within the last 6 months, which might affect the periodontal status
- Pregnant and lactating women
- Patients who had any periodontal treatment ≤ 12 months before the examination.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Israel · 1 center
- Dr Younis Mahmoud — Afula
Publications
- Schwarz F, Aoki A, Becker J, Sculean A. Laser application in non-surgical periodontal therapy: a systematic review. J Clin Periodontol. 2008 Sep;35(8 Suppl):29-44. doi: 10.1111/j.1600-051X.2008.01259.x. PMID 18724840
- Jia L, Jia J, Xie M, Zhang X, Li T, Shi L, Shi H, Zhang X. Clinical attachment level gain of lasers in scaling and root planing of chronic periodontitis: a network meta-analysis of randomized controlled clinical trials. Lasers Med Sci. 2020 Mar;35(2):473-485. doi: 10.1007/s10103-019-02875-5. Epub 2019 Nov 5. PMID 31691054
- Moritz A, Gutknecht N, Doertbudak O, Goharkhay K, Schoop U, Schauer P, Sperr W. Bacterial reduction in periodontal pockets through irradiation with a diode laser: a pilot study. J Clin Laser Med Surg. 1997 Feb;15(1):33-7. doi: 10.1089/clm.1997.15.33. PMID 9467340
- Aoki A, Sasaki KM, Watanabe H, Ishikawa I. Lasers in nonsurgical periodontal therapy. Periodontol 2000. 2004;36:59-97. doi: 10.1111/j.1600-0757.2004.03679.x. No abstract available. PMID 15330944
- Gojkov-Vukelic M, Hadzic S, Dedic A, Konjhodzic R, Beslagic E. Application of a diode laser in the reduction of targeted periodontal pathogens. Acta Inform Med. 2013 Dec;21(4):237-40. doi: 10.5455/aim.2013.21.237-240. Epub 2013 Dec 4. PMID 24554796
- Matarese G, Ramaglia L, Cicciu M, Cordasco G, Isola G. The Effects of Diode Laser Therapy as an Adjunct to Scaling and Root Planing in the Treatment of Aggressive Periodontitis: A 1-Year Randomized Controlled Clinical Trial. Photomed Laser Surg. 2017 Dec;35(12):702-709. doi: 10.1089/pho.2017.4288. Epub 2017 Sep 14. PMID 28945145
- Dukic W, Bago I, Aurer A, Roguljic M. Clinical effectiveness of diode laser therapy as an adjunct to non-surgical periodontal treatment: a randomized clinical study. J Periodontol. 2013 Aug;84(8):1111-7. doi: 10.1902/jop.2012.110708. Epub 2012 Oct 17. PMID 23075433
- De Micheli G, de Andrade AK, Alves VT, Seto M, Pannuti CM, Cai S. Efficacy of high intensity diode laser as an adjunct to non-surgical periodontal treatment: a randomized controlled trial. Lasers Med Sci. 2011 Jan;26(1):43-8. doi: 10.1007/s10103-009-0753-5. Epub 2010 Feb 4. PMID 20131073
Identifiers
NCT: NCT07446127 · 0011601-1