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Recruiting NCT07445555

Gingival Recessions in Orthodontically Treated and Untreated Adult Patients

Observational Gingival Recession Orthodontic Treatment

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Registration of parameters.
Who it may be relevant to
Registry conditions: Gingival Recession, Orthodontic Treatment. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Belgium
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Gingival Recessions in Orthodontically Treated and Untreated Adult Patients: a Prospective Study

Overview

To identify the predisposing parameters for gingival recessions in adult patients seeking orthodontic treatment. The ultimate aim is to provide a clinical guideline to estimate the risk of developing post-orthodontic gingival recessions.

Detailed description

The etiology of gingival recessions is yet to be fully understood and is very likely multifactorial, with the involved parameters not necessarily acting simultaneously or in equal extent. The most common etiologic factor would be dental plaque accumulation followed by traumatic tooth brushing, areas with thin, minimal or no keratinized tissue, smoking, malocclusion, dental trauma and high frenal attachment. The labial aspect of the mandibular incisors and maxillary molars is the most often affected by gingival recessions. These contributing factors identified in literature could be grouped in six main categories: age-related, population-related, site-related, mechanical factors, periodontal condition and iatrogenic factors, like orthodontic treatment.

Although quantifying the influence of each factor is very difficult, the association between gingival recessions and orthodontic treatment as an iatrogenic factor has been repeatedly suggested. Given the increasing amount of adult patients seeking orthodontic treatment, the aim of this study is to identify the predisposing parameters for gingival recessions in adult patients, seeking orthodontic treatment. The ultimate aim is to provide a clinical guideline to estimate the risk of developing post-orthodontic gingival recessions.

Interventions

  • Other Registration of parameters
    De gingival and occlusal parameters will be recorded for the 4 different cohort groups

Primary outcome measures

  • Gingival parameters [Time frame: 6 months]
  • Periodontal phenotype: [Time frame: 6 months]
  • Full Mouth Bleeding scores (FMBS) [Time frame: 6 months]
  • Full Mouth Plaque Score (FMPS) [Time frame: 6 months]
  • Occlusion [Time frame: 6 months]
  • Occlusal contact points [Time frame: 6 months]

Eligibility criteria

Inclusion criteria

  • Patients with or without previous history of orthodontic treatment with and without gingival recessions
  • ≥ 18 years old
  • American Society of Anesthesiologists Classification I or II

Exclusion criteria

  • Patients with history of periodontal disease
  • taking the following medication: anticoagulants, phenytoin, cyclosporine, nifedipine or calcium channel blockers
  • Patients with prior history of radio or chemotherapy
  • Pregnant or breastfeeding patients
  • Patients with agenesis of one or more lower incisors

Exclusion criteria

Patients with history of periodontal disease Patients taking the following medication: anticoagulants, phenytoin, cyclosporine, nifedipine or calcium channel blockers Patients with prior history of radio or chemotherapy Pregnant or breastfeeding patients Patients with agenesis of one or more lower incisors

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Belgium · 1 center
  • UZ Leuven — Leuven

Identifiers

NCT: NCT07445555 · S67563

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗