Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Preecalmpsia. Basic parameters: 20 years — 40 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia With Severe Features Undergoing Cesarean Delivery: A Prospective Observational Study
Overview
Preeclampsia with severe features remains a leading contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. It is defined by hypertension and involvement of multiple organ systems, including renal, hepatic, hematologic, and neurologic pathways. The interplay of endothelial dysfunction, capillary leakage, and disrupted fluid balance in these patients increases their susceptibility to perioperative pulmonary complications. Although respiratory complications in preeclampsia are clinically significant, the true incidence of postoperative diaphragmatic dysfunction in women with severe disease is not well established. Existing literature largely emphasizes general respiratory failure, pulmonary edema, or the need for mechanical ventilation, rather than specifically evaluating diaphragmatic performance with objective methods such as ultrasound. The current study sought to determine the incidence and identify risk factors for postoperative diaphragmatic dysfunction in women with severe preeclampsia following cesarean delivery.
Primary outcome measures
- The incidence of postoperative diaphragmatic dysfunction [Time frame: Diaphragmatic excursion is measured before and 24 hours after surgery.]
Secondary outcome measures (2)
- Percentage of change in DE [Time frame: 24 hours after surgery]
- Risk factors associated with postoperative diaphragmatic dysfunction [Time frame: 24 hours after surgery]
Eligibility criteria
Inclusion criteria
- Patients with severe preeclampsia undergoing cesarean section
- Gestational age > 32 weeks
Exclusion criteria
- • Age < 20 years.
- Diabetic
- Patients with neuromuscular diseases.
- Patient refusal.
- Contraindications to magnesium sulphate administration
- Inability to obtain adequate ultrasound views
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Egypt · 1 center
- Cairo University Hospitals — Cairo
Identifiers
NCT: NCT07443345 · N-62-2026