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Recruiting NCT07440615

Lower-Limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females

No phase Interventional Physical Performance Leg Muscle Mass Muscle Strength Aerobic Capacity

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Physical Performance Assessment.
Who it may be relevant to
Registry conditions: Physical Performance, Leg Muscle Mass, Muscle Strength, Aerobic Capacity. Basic parameters: 18 years — 30 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Relationship Between Lower-limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females.

Overview

The aim of this study will be to examine the relationship between leg muscle mass and muscle strength, aerobic capacity, anaerobic power, and jumping performance in young adults. In addition, these physical performance measures will be compared between male and female participants. Recreationally active young adults will be recruited to participate in the study. Body weight and leg muscle mass will be assessed using a body composition analyzer. Participants will perform isokinetic and isometric leg strength tests, an aerobic fitness test (VO₂max), an anaerobic power test (Wingate), and a countermovement jump (CMJ) test. This study aims to improve the understanding of the effects of leg muscle mass on physical performance and to identify possible differences between males and females. The findings are expected to contribute to exercise prescription, performance assessment, and future research in sports and health sciences.

Interventions

  • Other Physical Performance Assessment
    Muscle Isokinetic Strength Testing, Leg Muscle Mass, and Aerobic and Anaerobic Performance Testing, Contermovement Jump

Primary outcome measures

  • Leg Muscle Mass-Related Physical Performance Measures [Time frame: Baseline]
  • Muscle Isokinetic Strength [Time frame: Baseline]
  • Anaerobic Power [Time frame: Baseline]
  • Countremovement Jump [Time frame: Baseline]
  • Aerobic Capacity [Time frame: Baseline]
  • Muscle Isometric Strength [Time frame: Baseline]

Eligibility criteria

Inclusion criteria

  • absent of lower body injuries that could impact testing;
  • were moderately physically active
  • did not ingest ergogenic aids or stimulant drugs for at least 6 months prior to the start of the study.

Exclusion criteria

\-

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Basic science

Study locations

Turkey (Türkiye) · 1 center
  • Aeromedical Research and Training Center (ARTC) — Eskişehir

Publications

  • Amaral JF, Alvim FC, Castro EA, Doimo LA, Silva MV, Novo Junior JM. Influence of aging on isometric muscle strength, fat-free mass and electromyographic signal power of the upper and lower limbs in women. Braz J Phys Ther. 2014 Mar-Apr;18(2):183-90. doi: 10.1590/s1413-35552012005000145. Epub 2014 Mar 19. PMID 24676705
  • Boraczynski M, Boraczynski T, Podstawski R, Wojcik Z, Gronek P. Relationships Between Measures of Functional and Isometric Lower Body Strength, Aerobic Capacity, Anaerobic Power, Sprint and Countermovement Jump Performance in Professional Soccer Players. J Hum Kinet. 2020 Oct 31;75:161-175. doi: 10.2478/hukin-2020-0045. eCollection 2020 Oct. PMID 33312304
  • Bullo V, Roma E, Gobbo S, Duregon F, Bergamo M, Bianchini G, Doria E, Cugusi L, Blasio AD, Bocalini DS, Ermolao A, Bergamin M. Lower Limb Strength Profile in Elderly with Different Pathologies: Comparisons with Healthy Subjects. Geriatrics (Basel). 2020 Oct 22;5(4):83. doi: 10.3390/geriatrics5040083. PMID 33105620
  • Comfort P, McMahon JJ, Lake JP, Ripley NJ, Triplett NT, Haff GG. Relative strength explains the differences in multi-joint rapid force production between sexes. PLoS One. 2024 Feb 15;19(2):e0296877. doi: 10.1371/journal.pone.0296877. eCollection 2024. PMID 38359039
  • Cuesta-Vargas A, Gonzalez-Sanchez M. Correlation between architectural variables and torque in the erector spinae muscle during maximal isometric contraction. J Sports Sci. 2014;32(19):1797-804. doi: 10.1080/02640414.2014.924054. Epub 2014 Jun 6. PMID 24903060
  • Driller MW, Argus CK, Shing CM. The reliability of a 30-s sprint test on the Wattbike cycle ergometer. Int J Sports Physiol Perform. 2013 Jul;8(4):379-83. doi: 10.1123/ijspp.8.4.379. PMID 23863304
  • Farinatti P, Castinheiras Neto AG, Amorim PR. Oxygen Consumption and Substrate Utilization During and After Resistance Exercises Performed with Different Muscle Mass. Int J Exerc Sci. 2016 Jan 15;9(1):77-88. doi: 10.70252/AKBM3973. eCollection 2016. PMID 27293507
  • Harris-Love MO, Benson K, Leasure E, Adams B, McIntosh V. The Influence of Upper and Lower Extremity Strength on Performance-Based Sarcopenia Assessment Tests. J Funct Morphol Kinesiol. 2018 Dec;3(4):53. doi: 10.3390/jfmk3040053. Epub 2018 Nov 3. PMID 30533549

Identifiers

NCT: NCT07440615 · E-87914409-050.04-87583

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗