Antibacterial Effect and Postoperative Pain After Triton Irrigation Protocol in Necrotic Mandibular Molar
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: triton irrigation protocol, conventional irrigation group.
- Who it may be relevant to
- Registry conditions: Pulp Necrosis. Basic parameters: 18 years — 45 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Evaluation of Antibacterial Effect and Postoperative Pain Following Irrigation Protocol Using Triton in Necrotic Mandibular Molars. A Randomized Clinical Control Trial
Overview
This randomized clinical study evaluates the antibacterial effectiveness and postoperative pain following root canal irrigation using the Triton irrigation protocol in necrotic mandibular molars. Thirty-six patients requiring root canal treatment will be included. The study aims to compare bacterial reduction and postoperative pain outcomes after treatment. Results may help improve irrigation protocols and patient comfort during endodontic therapy.
Detailed description
Root canal disinfection is a critical factor affecting the success of endodontic treatment, especially in teeth with necrotic pulps. Irrigation protocols play an essential role in reducing bacterial load inside the root canal system. The Triton irrigation protocol has been introduced to enhance antimicrobial effectiveness and improve debris removal.
This randomized clinical trial will include 36 patients diagnosed with necrotic mandibular molars indicated for root canal treatment. Participants will receive treatment following the assigned irrigation protocol. Bacterial samples will be collected before and after irrigation to evaluate antibacterial effectiveness. Postoperative pain will be assessed using a standardized pain scale during the follow-up period.
The findings of this study are expected to provide clinical evidence regarding the effectiveness of the Triton irrigation protocol in improving disinfection outcomes and reducing postoperative discomfort
Interventions
- Procedure triton irrigation protocol
Root canal irrigation performed using Triton solution according to a standardized endodontic irrigation protocol during root canal treatment. - Procedure conventional irrigation group
Participants receive conventional root canal irrigation using standard irrigation solutions during chemo-mechanical preparation according to the routine clinical protocol.
Primary outcome measures
- antibacterial effect [Time frame: immediately after irrigation procedures]
Secondary outcome measures (1)
- postoperative pain intensity [Time frame: 6, 12, 24, and 48 hours after treatment]
Eligibility criteria
Inclusion criteria
- Patients aged 18-45 years with no sex predilection
- Medically free Patients with no systemic conditions that can affect post operative pain response.
- Patients should not be taking any pain medications 24 hours before intervention
- Positive patients' acceptance for participating in the study
- Patient able to sign informed consent
- Permanent mandibular molars diagnosis with pulpal necrosis with asymptomatic apical periodontitis.
- Mandibular molars without any anatomical variations or severe curvatures with mesial roots configuration weine class 3 and a distal root with 2 distal canals
Exclusion criteria
- Medically compromised patients
- Patients who have received antibiotic therapy within the last 2 weeks.
- Pregnant or lactating women.
- Patients with known allergy to any of the irrigants used.
- Patients with swelling or acute peri-apical abscess or fistulous tract.
- Teeth that have:
- Wide or open apex .
- Vital pulp tissue .
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Faculty of Oral and Dental Medicine , Future University in Egypt — Cairo
Identifiers
NCT: NCT07435883 · FUE.REC (17)/1-2026