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Recruiting NCT07434752

A Study to See if an Energy Drink With Caffeine and Green Tea Increases Fat Burning When Exercising

Phase IV Interventional Exercise

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Active (Green tea and caffeine), Placebo.
Who it may be relevant to
Registry conditions: Exercise. Basic parameters: 18 years — 45 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Australia
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Influence of Caffeine and Green Tea Extracts Consumption on Basal, Peri- and Post-exercise Fat Oxidation

Overview

The goal of this study is to evaluate the influence of consuming a drink containing a combination of caffeine and green tea extracts on fat oxidation responses at rest, during and after a period of endurance type exercise.

Detailed description

This study investigates whether consuming an energy drink containing caffeine and green tea extract before exercise increases fat burning (oxidation) compared with a placebo drink. Healthy, moderately active adults will attend three visits at clinic over 3-5 weeks. The first visit determines each participant's individual exercise intensity that maximises fat use during cycling. At two subsequent visits, participants will consume either the active drink or a placebo before completing a 30-minute cycling session at their personalised intensity. Fat and carbohydrate use, heart rate, blood pressure, and subjective responses will be measured at rest, during exercise, and after exercise using a double-blind, crossover design.

Interventions

  • Dietary supplement Active (Green tea and caffeine)
    Two 355 mL cans of "XS Energy + BURN" drink containing caffeine and green tea extract.
  • Other Placebo
    Two 355 mL cans of placebo drink but without the active ingredients (caffeine and green tea extract).

Primary outcome measures

  • Fat oxidation as measured by indirect calorimetry [Time frame: Baseline to 30 mins post exercise]
Secondary outcome measures (3)
  • Carbohydrate oxidation; indirect calorimetry [Time frame: Baseline to 30 mins post exercise]
  • Respiratory exchange ratio; indirect calorimetry [Time frame: Baseline to 30 mins post exercise]
  • Exercise efficiency; indirect calorimetry [Time frame: Baseline to 30 mins post exercise]

Eligibility criteria

Inclusion criteria

  • Passing the Exercise and Sport Science Australia adult pre-exercise screening system (APSS) stage 1 \& 2 (see appendix 4).
  • Between the ages of 18 and 45,
  • Not sedentary, and not completing more than 150 minutes of low and/or moderate and/or or vigorous intensity endurance exercise a week,
  • Ability to commit to in principle fulfilment of all 3 trial visits,
  • No history of coagulopathy e.g., DVT, stroke,
  • No known heart disease,
  • No known pancreatic insufficiency,
  • No known inflammatory bowel disease, or prior bowel resection or bypass surgery (excluding gastric banding and sleeve),
  • BMI of 22.0 to 34.9 kg/m2,
  • No known allergies to caffeine or green tea extract,
  • No known type I or II diabetes,
  • No uncontrolled concurrent illness,
  • No known current pregnancy or breastfeeding women
  • No current regular consumption of supplements (>2 times a week) or foods and drinks containing caffeine and/or green tea extracts (>2 times per day, weekly).
  • Agree not to consume caffeine for 12-hours prior to the clinic visit.

Exclusion criteria

  • Triggering any of the exclusion screening criteria as outlined below, and in compliment with the Exercise and Sport Science Australia adult pre-exercise screening system (APSS).
  • Under the age of 18 or over the age of 45,
  • Sedentary, or completing over 150 minutes of low and/or moderate and/or or vigorous intensity endurance exercise a week,
  • Inability to commit to in principle fulfilment of all 3 trial visits,
  • History of coagulopathy e.g., DVT, stroke,
  • Known heart disease,
  • Known pancreatic insufficiency,
  • Known inflammatory bowel disease, or prior bowel resection or bypass surgery (excluding gastric banding and sleeve),
  • BMI < 22.0 or > 34.9 kg/m2,
  • Known allergies to caffeine or green tea extract,
  • Known type I or II diabetes,
  • Uncontrolled concurrent illness,
  • Taking GLP-1 agonists, caffeine, or any other medication known to affect metabolism.
  • Known current pregnancy or breastfeeding women.
  • Currently regularly consuming supplements, foods or drinks containing a caffeine and green tea extract blend, or not willing to abstain for the study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Crossover
Masking
Quadruple blind
Primary purpose
Treatment

Study locations

Australia · 1 center
  • Griffith University, Gold Coast Campus — Southport

Identifiers

NCT: NCT07434752 · GRIFEX

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗