Frequency of Electrical Acupoint Stimulation on Hypotension During Induction
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: electrical acupoint stimulation, electrodes pasted, high-frequency electrical stimulation, low-frequency electrical stimulation.
- Who it may be relevant to
- Registry conditions: Anesthesia, Hypotension. Basic parameters: from 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
The Influence of Electrical Acupoint Stimulation at Different Frequencies on Hemodynamics During Anesthesia Induction
Overview
Within 30 minutes before anesthesia, acupoint electrical stimulation at different frequencies were applied at Neiguan and Jian Shi. The changes in blood pressure during the anesthesia induction period were compared between the high-frequency group and the low-frequency group.
Interventions
- Other electrical acupoint stimulation
electrical acupoint stimulation are administered at Neiguan and Jian Shi. The stimulation starts at 15 minutes before anesthesia induction and ends at 15 minutes after anesthesia induction. - Other electrodes pasted
Electrodes are pasted at Neiguan and Jianshi - Other high-frequency electrical stimulation
The frequency of electrical stimulation is 100Hz - Other low-frequency electrical stimulation
The frequency of electrical stimulation is 2Hz
Primary outcome measures
- incidence of hypotension [Time frame: from start of anesthesia induction to 15 minutes after induction]
Secondary outcome measures (5)
- The area under the curve representing the change in mean arterial pressure during the induction period relative to the baseline. [Time frame: from start of induction to 15 minutes after induction]
- The dosage of vasoactive drugs [Time frame: from start of induction to 15 minutes after induction]
- lowest MAP [Time frame: from start of induction to 15 minutes after induction]
- standard deviation of R-R intervals (SDRR) [Time frame: from start of induction to 15 minutes after induction]
- ratio of low-frequency HRV/high-frequency HRV (LF/HF ratio) [Time frame: from start of induction to 15 minutes after induction]
Eligibility criteria
Inclusion criteria
- aged over 65 yrs old
- scheduled for surgery under general anesthesia
Exclusion criteria
- American society of anesthesiologists status over 3
- severe cardiac or respiratory dysfunction
- severe cardiac arrhythmia
- uncontrolled diabetes
- systolic arterial pressure over 180 mmHg
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Triple blind
- Primary purpose
- Treatment
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Kaduk K, Petrella A, Muller SJ, Koenig J, Kroemer NB. Non-Invasive Auricular Vagus Nerve Stimulation Decreases Heart Rate Variability Independent of Caloric Load. Psychophysiology. 2025 Feb;62(2):e70017. doi: 10.1111/psyp.70017. PMID 40007175
- Chaitman BR, Bitar SR. Is ST segment elevation non-Q-wave myocardial infarction after thrombolytic therapy a new clinical entity that requires an invasive management strategy? J Am Coll Cardiol. 2001 Jan;37(1):26-9. doi: 10.1016/s0735-1097(00)01053-6. No abstract available. PMID 11153749
Identifiers
NCT: NCT07433218 · XJH-A-20260220