Clinical and Radiographic Outcomes of Alveolar Ridge Preservation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Alveolar Ridge Preservation. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Clinical and Radiographic Outcomes of Alveolar Ridge Preservation for Implant-prosthetic Rehabilitation in a Hospital Setting: a Prospective Study
Overview
Dental implants are considered a predictable rehabilitative option following tooth extraction or in cases of missing teeth. In some situations, the inevitable alveolar ridge resorption that occurs after extraction may make the placement of standard-diameter (\>3.5 mm) or standard-length implants difficult or even impossible without advanced bone augmentation procedures. To counteract post-extraction volumetric bone contraction, alveolar ridge preservation can be performed, consisting of placing a bone graft within the socket walls immediately after tooth extraction. Although this procedure cannot completely prevent dimensional changes, it has been shown to significantly reduce both horizontal and vertical ridge resorption, as reported in the scientific literature. However, there is a lack of clinical and radiographic studies evaluating the outcomes of implant rehabilitation following alveolar ridge preservation with standard-dimension implants in a hospital-based setting.
Primary outcome measures
- Volumetric analysis [Time frame: From tooth extraction to 6 months of follow up.]
Secondary outcome measures (12)
- Esthetic evaluation [Time frame: From tooth extraction to 5 years of follow-up]
- Implant success rate [Time frame: From tooth extraction to 5 years of follow up]
- Implant survival rate [Time frame: From tooth extraction to 5 years follow up]
- Prosthesis success rate [Time frame: From tooth extraction to 5 years of follow up]
- Prosthesis survival rate [Time frame: From tooth extraction to 5 years of follow up]
- Patient-Reported Outcome Measures [Time frame: From tooth extraction to 5 years of follow up]
- Diabetes [Time frame: From tooth extraction to 5 years of follow up]
- Glycated hemoglobin level [Time frame: From tooth extraction to 5 years of follow up]
- Correlation of medications relevant to bone/soft tissue metabolism with implant health [Time frame: From tooth extraction to 5 years of follow up]
- Correlation between osteoporosis status and implant health [Time frame: From tooth extraction to 5 years of follow up]
- Correlation between cardiovascular disease and implant health [Time frame: From tooth extraction to 5 years of follow up]
- Complete Blood Count [Time frame: From tooth extraaction to 5 years of follow up]
Eligibility criteria
Inclusion criteria
- Patients requiring alveolar ridge preservation procedures prior to implant rehabilitation of edentulous sites;
- Age > 18;
- Achievement of FMPS and FMBS ≤ 15%;
- Signed written informed consent to participate in the study.
Exclusion criteria
- Uncontrolled diabetes or hypertension;
- Uncontrolled periodontal disease;
- Inability to perform consistent and continuous follow-up;
- Pregnancy or breastfeeding;
- Inability to provide written informed consent.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-only
Study locations
Italy · 1 center
- Catholic University of the Sacred Heart — Roma
Publications
- Sandoli Arroteia L, Lopes MP, Rea MT, Vieira E Oliveira TR, Oliveira ML, de Faveri M, Santamaria MP, Queiroz LA, Casati MZ, Casarin RCV. Dimensional Changes After Different Alveolar Ridge Preservation Techniques for Posterior Region: A Randomised Controlled Clinical Trial. J Clin Periodontol. 2025 Nov;52(11):1584-1594. doi: 10.1111/jcpe.70004. Epub 2025 Aug 5. PMID 40762250
- Araujo M, Linder E, Wennstrom J, Lindhe J. The influence of Bio-Oss Collagen on healing of an extraction socket: an experimental study in the dog. Int J Periodontics Restorative Dent. 2008 Apr;28(2):123-35. PMID 18546808
- Araujo MG, Lindhe J. Dimensional ridge alterations following tooth extraction. An experimental study in the dog. J Clin Periodontol. 2005 Feb;32(2):212-8. doi: 10.1111/j.1600-051X.2005.00642.x. PMID 15691354
Identifiers
NCT: NCT07427784 · 8085