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Not yet recruiting NCT07427095

The Relationship Between Ultra-Processed Food Consumption and Oral Health

— Observational Ultra-processed Food

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Ultra-processed Food. Basic parameters: 18 years — 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Turkey (Türkiye)
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Investigating the Relationship Between Ultra-Processed Food Consumption and Caries and Periodontal Disease

Overview

The goal of this observational study is to examine the potential relationship between ultra-processed food consumption and the presence of dental caries and periodontal disease, and to evaluate the role of the Ultra-Processed Food Index (UPFI) in this association. The main question it aims to answer is: Does increased consumption of ultra-processed foods raise the risk or severity of dental caries and periodontal disease in individuals? Participants will include individuals within a specified age range who voluntarily agree to participate in the study. Oral health status will be assessed through standard clinical parameters, including the presence of caries, plaque index, probing pocket depth, clinical attachment loss, and bleeding on probing. Dietary habits will be evaluated using a validated food frequency questionnaire, and individual UPFI scores will be calculated. The study will aim to observe and analyze the effects of ultra-processed food consumption on oral health outcomes.

Detailed description

This observational study will aim to investigate the association between ultra-processed food consumption and oral health outcomes, specifically focusing on dental caries and periodontal disease. Participants will include individuals within a defined age range who consent to take part in the study. Oral health status will be clinically assessed using standard parameters such as the presence of carious lesions, plaque index, probing pocket depth, clinical attachment loss, and bleeding on probing. Dietary intake will be evaluated using a validated food frequency questionnaire, and individual Ultra-Processed Food Index (UPFI) scores will be calculated. The study will analyze whether a higher intake of ultra-processed foods is associated with increased risk or severity of dental caries and periodontal disease. Findings from this study are expected to contribute to a better understanding of the impact of modern dietary patterns on oral health and highlight the importance of nutritional strategies in preventive dentistry.

Primary outcome measures

  • Ultra-Processed Food Index (UPFI) [Time frame: Day 1]
Secondary outcome measures (12)
  • Decayed Missing Filled Tooth (DMFT) Index [Time frame: Day 1]
  • Community Periodontal Index (CPI) Score [Time frame: Day 1]
  • Age [Time frame: Day 1]
  • Waist Circumference [Time frame: Day 1]
  • Gender [Time frame: Day 1]
  • Weight satisfaction [Time frame: Day 1]
  • Educational level [Time frame: Day 1]
  • Income level [Time frame: Day 1]
  • Smoking status [Time frame: Day 1]
  • Toothbrushing frequency [Time frame: Day 1]
  • Decayed Missing Filled Tooth (DMFT) Index [Time frame: Day 1]
  • Decayed Missing Filled Tooth (DMFT) Index [Time frame: Day 1]

Eligibility criteria

Inclusion criteria

  • Individuals between the ages of 18 and 65,
  • Individuals with at least 20 teeth,
  • Not having received periodontal treatment in the last 6 months,
  • Not having taken antibiotics, steroids, and/or nonsteroidal anti-inflammatory drugs in the last 3 weeks,
  • Not having any autoimmune disease, osteoporosis, or cancer,
  • Not using immunosuppressive drugs, oral contraceptives, or bisphosphonates,
  • Not being pregnant,
  • Not having an active infectious disease (acute hepatitis, tuberculosis, AIDS),
  • Not using chronic medications that affect periodontal tissues (cyclosporine A, Phenytoin),
  • Not having taken antioxidant supplements in the last 6 months.

Exclusion criteria

  • Patients with endocrine or genetic disorders such as hypothyroidism, type 1 diabetes mellitus, or Cushing's syndrome
  • Patients with active infectious disease
  • Patients taking medications that may affect periodontal tissues
  • Patients who have recently taken antibiotics (within 4 months)
  • Patients with alcohol/drug use
  • Patients with psychological disorders
  • Patients with eating disorders, dementia
  • Patients who are pregnant or breastfeeding
  • Patients with any food allergies
  • Patients who do not sign the informed consent form

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-only

Study locations

Turkey (Türkiye) · 1 center
  • Department of Periodontology of the Faculty of Dentistry of Recep Tayyip Erdogan Universit — Rize

Identifiers

NCT: NCT07427095 · UPHOralHealth11/25

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗