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Recruiting NCT07425496

To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictive Value in Improving Postoperative Outcomes.

Observational Cataract Glaucoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: disposable Deltran I pressure sensor.
Who it may be relevant to
Registry conditions: Cataract, Glaucoma. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Dynamic Ocular Tonometry Study During Intraocular Surgery

Overview

The objective of this study is to evaluate ocular outflow dynamics of the eye using intraoperative tonographic biometry and assess its predictive value in improving postoperative outcomes.

Detailed description

This study proposes to measure the intraocular pressure (IOP), ocular fluid dynamics and outflow homeostasis in patients undergoing intraocular surgery to understand how post-operative surgical success can be optimized and complications prevented.

This is a prospective observational study, single study arm and at a single-site. Recruitment will be from physicians affiliated with the Mount Sinai Health System who are performing intraocular surgeries, such as cataract and/or glaucoma surgeries. Intraocular pressure measurements will be taken using an FDA-registered, sterile, single-use, disposable Deltran I pressure sensor designed for measuring physiological pressures of the body to obtain concomitant intraocular measurement and outflow capacity calculation during the surgery. Monitoring intra ocular pressure postoperatively for up to 90 days.

Interventions

  • Diagnostic test disposable Deltran I pressure sensor
    Intraocular pressure measurements will be taken using an FDA-registered, sterile, single-use, disposable Deltran I pressure sensor designed for measuring physiological pressures of the body.

Primary outcome measures

  • Intraocular Pressure (IOP) measurement calculation during surgery. [Time frame: 90 days]
  • Outflow capacity calculation during surgery [Time frame: 90 days]
Secondary outcome measures (1)
  • Rate of intraoperative and postoperative complications. [Time frame: 90 days]

Eligibility criteria

Inclusion criteria

  • Individuals undergoing cataract and/or glaucoma surgery in the Mount Sinai Health System.

Exclusion criteria

  • Individuals less than 18 years old, pregnant women, those without capacity to make their own decisions, and prisoners.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • New York Eye and Ear Infirmary of Mount Sinai — New York

Publications

  • Sherwood JM, Reina-Torres E, Bertrand JA, Rowe B, Overby DR. Measurement of Outflow Facility Using iPerfusion. PLoS One. 2016 Mar 7;11(3):e0150694. doi: 10.1371/journal.pone.0150694. eCollection 2016. PMID 26949939

Identifiers

NCT: NCT07425496 · 23-00501

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗