Not yet recruiting NCT07424456

Comparison Between Triphasic CT Abdomen and EUS-FNB in Characterization of Pancreatic Lesion

— Observational EUS Guided Biopsy CT Scan Pancreatic Lesions Located at the Body or the Tail

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied: The protocol lists: Full clinical history (pain, jaundice, weight loss, pancreatitis history). Physical examination with focus on abdominal and systemic findings..
Who it may be relevant to: Registry conditions: EUS Guided Biopsy, CT Scan, Pancreatic Lesions Located at the Body or the Tail. Basic parameters: from 18 years · All.
What needs checking: Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place: Center list to be confirmed — check the primary protocol.
Next step: Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

evaluate the relationship between triphasic CT and EUS findings and the characterization of pancreatic lesions.

Detailed description

Comparison Between Triphasic CT and EUS-FNB in characterization of Pancreatic Lesions

Diagnostic test Full clinical history (pain, jaundice, weight loss, pancreatitis history). Physical examination with focus on abdominal and systemic findings.
Full clinical history (pain, jaundice, weight loss, pancreatitis history). Physical examination with focus on abdominal and systemic findings.

Diagnostic accuracy of triphasic CT compared to EUS-guided biopsy in differentiating benign from malignant pancreatic lesions. [Time frame: one year]

\*Adult patients (age>18 years) presenting with focal pancreatic lesions detected on initial imaging.

Patients referred for further evaluation by triphasic CT and/or EUS-guided biopsy.
Patients able to provide informed consent

Known metastatic disease at presentation.
Contraindications to contrast-enhanced CT (e.g. severe renal impairment, contrast allergy)
Contraindications to EUS or biopsy (e.g., coagulopathy uncorrected, severe cardiopulmonary instability).
Pregnancy.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Center list to be confirmed — check the primary protocol.

Iglesias Garcia J, Larino Noia J, Dominguez Munoz JE. Endoscopic ultrasound in the diagnosis and staging of pancreatic cancer. Rev Esp Enferm Dig. 2009 Sep;101(9):631-8. doi: 10.4321/s1130-01082009000900006. PMID 19803666
Öztürk B, Ekmen N, et al. The diagnostic role of endoscopic ultrasonography, CT, and MRI in pancreatic cystic lesions. J Clin Med Kaz. 2021;18(4):71-80.
Chen J, Sahai AV, et al. Diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration in pancreatic tumors. BMC Gastroenterol. 2012;12:125.
Chatterjee A, Shah J. Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma. Diagnostics (Basel). 2023 Dec 28;14(1):78. doi: 10.3390/diagnostics14010078. PMID 38201387

NCT: NCT07424456 · Triphasic CT vs EUS-FNB