Recruiting NCT07419997
A Multicenter, Retrospective, Observational Cohort Study on Intravenous Thrombolysis Beyond the Time Window for Acute Ischemic Stroke
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Stroke. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
A multicenter, retrospective, observational cohort study on intravenous thrombolysis beyond the time window for acute ischemic stroke
Primary outcome measures
- Proportion of study participants with mRS scores of 0 - 1 [Time frame: at 90 (±7) days]
Secondary outcome measures (5)
- Distribution of mRS scores ranging from 0 to 6 [Time frame: at 90 (±7) days]
- Proportion of study participants with mRS scores of 0 - 2 [Time frame: at 90 (±7) days]
- The proportion of study participants with a NIHSS score of ≤1 or a decrease of ≥8 points compared to the baseline [Time frame: at 24 (±12) hours]
- mortality rate [Time frame: at 90 (±7) days]
- Symptomatic intracranial hemorrhage [Time frame: within 36 hours]
Eligibility criteria
- Patients with acute ischemic stroke, regardless of gender;
- Age ≥ 18 years old;
- Time from onset to treatment within 4.5 - 24 hours (the onset time refers to the last time when they appeared normal);
- Complete relevant clinical data (including gender, age, mRS, NIHSS, etc.).
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Xuanwu Hospital Capital Medical University, Beijing, Beijing 100053 — Beijing
Identifiers
NCT: NCT07419997 · XMEC-2025-006