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Not yet recruiting NCT07418307

Comparison Between Combined Biceps Femoris Short Head Block and Adductor Canal Block Versus Genicular Nerve Block

No phase Interventional Knee Arthroplasty, Total

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Combined biceps femoris short head block and adductor canal block, Genicular nerve block.
Who it may be relevant to
Registry conditions: Knee Arthroplasty, Total. Basic parameters: from 65 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Enhanced Analgesia in Elderly After Total Knee Arthroplasty Using Combined Biceps Femoris Short Head Block and Adductor Canal Block Versus Genicular Nerve Block

Overview

The purpose of this study is to compare the analgesic outcomes (time to first analgesic request, total amount of analgesic consumption, and pain scores) following total knee arthroplasty by either combined biceps femoris short head block and adductor canal block or genicular nerve block in elderly patients.

Interventions

  • Other Combined biceps femoris short head block and adductor canal block
    Adductor Canal Block high-frequency probe will be placed transversely on the anterior thigh midpoint between inguinal crease and medial condyle (depth 3-5 cm). The needle will be advanced in-plane from lateral to medial through sartorius or vastus medialis muscle toward the femoral artery. Then (10 ml of 0.25% bupivacaine and 2 mg dexamethasone) will be injected after negative aspiration, with confirming spread around the artery without vascular puncture. Biceps femoris short head block The pro
  • Other Genicular nerve block
    Position the patient will be placed in supine position with the knee slightly flexed via a pillow in the popliteal fossa. Use a high-frequency linear ultrasound transducer. Superolateral genicular nerve (SLGN): the transducer will be placed coronally over lateral femoral epicondyle, with sliding proximally to femur metaphysis; identifying artery between vastus lateralis fascia and bone. Superomedial genicular nerve (SMGN): the transducer will be placed coronally over medial femoral epicondyle,

Primary outcome measures

  • Time of first rescue analgesia (naluphine) [Time frame: 24 hours postoperative]
Secondary outcome measures (6)
  • block performance time [Time frame: time of performance of the block]
  • Pain intensity [Time frame: 30 minutesn2, 4, 8, 12, 18 , and 24 hours postoperative]
  • Total amount of rescue analgesia (nalbuphine) [Time frame: first 24 hours postoperative]
  • assess functional recovery [Time frame: at 12 hours and 24 hours postoperative]
  • patient's satisfaction [Time frame: 24 hours postoperative]
  • Block related complications [Time frame: 24 hours postoperative]

Eligibility criteria

Inclusion criteria

  • patient acceptance
  • Physical status: ASA I, II and Ⅲ.
  • Body mass index (BMI): 18.5 - 35 kg/m2.
  • Type of operations: total knee arthroplasty.

Exclusion criteria

  • Known hypersensitivity to dexamethasone or bupivacaine.
  • Coagulation disorders or taking drugs affect surgical hemostasis.
  • Patients with pre-existing neurological deficits.
  • Uncooperative patient or with altered mental status.
  • Patient with advanced cardiovascular or respiratory diseases or uncontrolled diabetes

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Faculty of Medicine,Zagazig University — Zagazig

Publications

  • You D, Qin L, Li K, Li D, Zhao G, Li L. A meta-analysis on advantages of peripheral nerve block post-total knee arthroplasty. Korean J Pain. 2021 Jul 1;34(3):271-287. doi: 10.3344/kjp.2021.34.3.271. PMID 34193634

Identifiers

NCT: NCT07418307 · ZU-IRB#2002/28-Jan-2026

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗