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Not yet recruiting NCT07416084

Comparison of Hypotension After Spinal Anesthesia With Hyperbaric Vs Isobaric Bupivacaine in Elective Cesarean After Colloid Preloading.

Phase II Interventional Hypotension After Spinal Anesthesia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Spinal anesthesia with hyperbaric bupivacaine, Spinal anesthesia with isobaric bupivacaine.
Who it may be relevant to
Registry conditions: Hypotension After Spinal Anesthesia. Basic parameters: from 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Pakistan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Comparison of Maternal Hypotension After Spinal Anesthesia With Hyperbaric Bupivacaine Vs Isobaric Bupivacaine in Elective Cesarean Section With Colloid Preloading

Overview

To assess the hemodynamic difference after spinal anesthesia with hyperbaric bupivacaine and isobaric bupivacaine in elective cesarean section

Interventions

  • Drug Spinal anesthesia with hyperbaric bupivacaine
    Spinal anesthesia with hyperbaric bupivacaine according to height
  • Drug Spinal anesthesia with isobaric bupivacaine
    Spinal anesthesia with Isobaric bupivacaine according to height

Primary outcome measures

  • Maternal hypotension [Time frame: Baseline]
Secondary outcome measures (6)
  • Maternal heart rate trend [Time frame: Baseline]
  • Use of vasopressors [Time frame: Baseline]
  • Nausea and vomiting [Time frame: Baseline]
  • APGAR score [Time frame: Baseline]
  • Conversion to general anesthesia [Time frame: Baseline]
  • Maternal MAP trend [Time frame: Baseline]

Eligibility criteria

Inclusion criteria

  • ASA II parturient with normal pregnancy Parturients undergoing elective cesarean section under spinal anesthesia Parturient refusing normal trial of labor, planned for ELLSCS under spinal anesthesia

Exclusion criteria

  • Patient refusal Parturient with known drug allergy to local anesthetics Parturients undergoing emergency cesarean section Spinal anesthesia converted to general anesthesia.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Supportive care

Study locations

Pakistan · 1 center
  • Liaquat National Hospital and Medical College — Karachi

Identifiers

NCT: NCT07416084 · 1327-2026-LNH-ERC

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗